Department of Chemistry, Tarbiat Modares University, Tehran, Iran.
Mol Divers. 2012 Nov;16(4):651-7. doi: 10.1007/s11030-012-9393-y. Epub 2012 Sep 16.
The reaction between ketenimine intermediates [generated from terminal alkynes and sulfonyl azides], diethyl azadicarboxylate, and sodium arylsulfinates in N, N-dimethylformamide at room temperature, affords ethyl 2,3-dihydro-3-oxo-4-phenyl-2-tosyl-5-(tosylamino)pyrazole-1-carboxylates in moderate-to-good yields. When diisopropyl azadicarboxylate was used as the ester component, diisopropyl 1-arylsulfonyl-2-{[aryl(alkyl)sulfonyl]-2-phenylethanimidoyl}-1,2-hydrazinedicarboxylates were obtained.
酮亚胺中间体[由末端炔烃和磺酰基叠氮化物生成]、二乙基偶氮二羧酸酯和苯亚磺酸钠在 N，N-二甲基甲酰胺中于室温下反应，可得到中等至良好收率的乙基 2,3-二氢-3-氧代-4-苯基-2-对甲苯磺酰基-5-(对甲苯磺酰氨基)吡唑-1-羧酸酯。当使用二异丙基偶氮二羧酸酯作为酯组分时，可得到二异丙基 1-芳基磺酰基-2-[[芳基(烷基)磺酰基]-2-苯乙亚胺酰基]-1,2-二氢肼二羧酸酯。
