Department of Psychobiology, Institute of Neurosciences, Center for Biomedical Research (CIBM), University of Granada, Granada 18071, Spain.
Learn Mem. 2012 Sep 14;19(10):444-8. doi: 10.1101/lm.027003.112.
Previous work on the effect of aging on spontaneous object recognition (SOR) memory tasks in rats has yielded controversial results. Although the results at long-retention intervals are consistent, conflicting results have been reported at shorter delays. We have assessed the potential relevance of the type of object used in the performance of aged rats in SOR tasks. Using standard objects, 24-mo-old rats did not exhibit retention impairment at a 1-h delay. At this retention interval no differences between young and old rats were found in a high-similarity SOR task, but aged rats exhibited deficits when clearly different complex forms were applied.
先前关于衰老对大鼠自发物体识别（SOR）记忆任务影响的研究结果存在争议。尽管长时距的结果是一致的，但在较短的延迟时间内却报告了相互矛盾的结果。我们评估了在 SOR 任务中使用的物体类型对老年大鼠表现的潜在相关性。使用标准物体，24 月龄大鼠在 1 小时延迟时没有表现出记忆损伤。在这个保留间隔内，在高相似性 SOR 任务中，年轻和老年大鼠之间没有差异，但当应用明显不同的复杂形式时，老年大鼠表现出缺陷。
