Teka Abaynesh, Kibatu Girma
University of Bahir Dar, Biological Inorganic Chemistry, P.O.Box-79, Bahir Dar, Ethiopia.
Ethiop J Health Sci. 2012 Mar;22(1):19-26.
Medical laboratories play essential roles in measurements of substances in body fluids for the purpose of diagnosis, treatment, prevention, and for greater understanding of the disease process. Thus, data generated from have to be reliable for which strict quality control, management and assurance are maintained. The aim of this study is to assess the accuracy and precision of clinical chemistry laboratories in western region of Amhara national regional state of Ethiopia in testing liver and kidney functions.
Eight laboratories in hospitals and a Regional Health Research Laboratory Center participated in this study from February to March, 2011. Each participant was requested to measure six specimens for six chemistry tests from two control samples. Three hundred twenty four test results to be reported from all participant laboratories, if all measurements can be made, were designed to be collected and statistically evaluated.
None of the study subject laboratories could deliver all the six tests for estimation of both liver and renal functions simultaneously during the study period. Only 213 values from the expected 324 values were reported and about 65 % of the 213 values reported fell outside of the allowable limits of errors for the chemistry tests of the control specimen used.
This study finding showed that there were lack of accuracy and precision in chemistry measurements. A regular survey on medical laboratories should be conducted questioning the accuracy and precision of their analyses in order to sustain improvements in the quality of services provided by participating laboratories for the benefit of patients. Laboratory Quality Management Systems appreciate the need for regular quality control and quality assessment schemes in medical laboratories.
医学实验室在测量体液中的物质以用于诊断、治疗、预防以及更深入了解疾病过程方面发挥着至关重要的作用。因此，所产生的数据必须可靠，为此要维持严格的质量控制、管理和保证。本研究的目的是评估埃塞俄比亚阿姆哈拉民族州西部地区临床化学实验室在检测肝肾功能方面的准确性和精密度。
2011年2月至3月，八家医院实验室和一个区域卫生研究实验室中心参与了本研究。要求每位参与者对来自两个对照样本的六项化学检测项目测量六个标本。如果所有测量都能完成，计划收集所有参与实验室要报告的324个检测结果并进行统计学评估。
在研究期间，没有一个研究对象实验室能够同时完成所有六项用于评估肝肾功能的检测。仅报告了预期324个值中的213个值，并且所报告的这213个值中约65%超出了所用对照样本化学检测的允许误差范围。
本研究结果表明化学测量缺乏准确性和精密度。应该对医学实验室进行定期调查，质疑其分析的准确性和精密度，以便为了患者的利益维持参与实验室所提供服务质量的改进。实验室质量管理体系认识到医学实验室定期质量控制和质量评估方案的必要性。
