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采用阴囊皮瓣重建术治疗阴茎阴囊部外 Paget 病广泛局部切除术后的缺损。

Reconstruction with scrotal skin flaps after wide local resection of penoscrotal extramammary Paget's disease.

机构信息

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.

出版信息

BJU Int. 2012 Dec;110(11 Pt C):E1121-4. doi: 10.1111/j.1464-410X.2012.11491.x. Epub 2012 Sep 18.

DOI:10.1111/j.1464-410X.2012.11491.x
PMID:22985467
Abstract

UNLABELLED

Study Type--Therapy (case series) Level of Evidence 4. What's known on the subject? and What does the study add? Both the treatment and reconstruction after resection of penoscrotal extramammary Paget's disease (EMPD) are of concern among oncological urologists. Reconstruction of large skin defects after wide local resection of this disease remains challenging and skilled work. For the first time, by using scrotal skin flaps, we have introduced an effective and reliable procedure into the new area of reconstruction for penoscrotal EMPD in selected patients, with satisfactory functional and aesthetic results.

OBJECTIVE

• To introduce an effective procedure for reconstruction of large skin defects after wide local resection of penoscrotal extramammary Paget's disease (EMPD) in selected patients using scrotal skin flaps without compromising oncological control.

PATIENTS AND METHODS

• From January to June 2010 this procedure was carried out in five selected patients with penoscrotal EMPD who underwent wide local resection with subsequent reconstruction using scrotal skin flaps. • Patient demographics, lesion characteristics, surgical margins and outcomes were evaluated. • Skin defects covered 48-96 cm(2) (median = 72 cm(2)). The median (range) duration of follow-up was 24 (22-27) months.

RESULTS

• Flaps survived with satisfactory functional and aesthetic results. • All patients survived without local or systemic recurrence of tumour.

CONCLUSIONS

• Wide local resection can provide cure in superficial penoscrotal EMPD. • The described method using scrotal skin flaps seems to be a safe and effective procedure for the reconstruction of large defects.

摘要

目的

• 介绍一种在不影响肿瘤控制的情况下,使用阴囊皮瓣为选定的患者重建广泛局部切除术后巨大的阴-阴囊外佩吉特病(EMPD)皮肤缺损的有效方法。

患者和方法

• 2010 年 1 月至 6 月,对 5 例接受广泛局部切除术并随后使用阴囊皮瓣进行重建的阴-阴囊 EMPD 患者实施了该手术。• 评估了患者的人口统计学特征、病变特征、手术切缘和结果。• 皮肤缺损面积为 48-96cm²(中位数=72cm²)。中位(范围)随访时间为 24 (22-27)个月。

结果

• 皮瓣存活,功能和美学效果满意。• 所有患者均无肿瘤局部或全身复发而存活。

结论

• 广泛局部切除术可治愈表浅的阴-阴囊 EMPD。• 采用阴囊皮瓣的描述方法似乎是重建巨大缺损的一种安全有效的方法。

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