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评价 Dietl 危象患者的分肾功能和肾图模式。

Evaluation of differential renal function and renographic patterns in patients with dietl crisis.

机构信息

Children's National Medical Center, Washington, DC, USA.

出版信息

J Urol. 2013 Feb;189(2):684-9. doi: 10.1016/j.juro.2012.09.051. Epub 2012 Oct 8.

Abstract

PURPOSE

We analyzed preoperative and postoperative differential renal function and characterized the renographic findings in patients with ureteropelvic junction obstruction associated with Dietl crisis.

MATERIALS AND METHODS

Patients with Dietl crisis who underwent pyeloplasty between January 2004 and December 2010 were classified by renographic presentation. Patients in group 1 were diagnosed with cortical retention, those in group 2 had an initial obstructed scan (T1/2 of 20 minutes or more and no cortical retention) and those in group 3 had an initial nondiagnostic scan (T1/2 of less than 20 minutes and no cortical retention). Renographic parameters were used to analyze each group.

RESULTS

A total of 59 patients met criteria for study inclusion. The 13 patients in group 1 demonstrated the most significant recovery of function after pyeloplasty (mean differential renal function change 13.59%). The 38 patients in group 2 exhibited a mean differential renal function change of 43.06% (range 20% to 54.6%) and mean preoperative T1/2 of 64.31 minutes. Pyeloplasty was performed in all 8 patients in group 3 based on subsequent diagnostic scan (4 patients) or increased hydronephrosis on other imaging associated with further symptomatic episodes (4). Initial renographic patterns noted in group 3 included biphasic curves, diminished clearance after 15 minutes upright or symptoms despite nonobstructive drainage.

CONCLUSIONS

Interpretation of diuretic renography requires the assimilation of multiple parameters since patients with Dietl crisis can exhibit variability in renographic patterns due to the intermittent nature of ureteropelvic junction obstruction. Cortical retention represents a specific and pathognomic finding of acute ureteropelvic junction obstruction. With appropriate evaluation of these parameters, obstruction can be reliably diagnosed and appropriate surgical candidates chosen.

摘要

目的

我们分析了肾盂输尿管连接部梗阻伴 Dietl 危机患者的术前和术后分肾功能,并对其肾图表现进行了特征描述。

材料与方法

回顾性分析 2004 年 1 月至 2010 年 12 月间因肾盂输尿管连接部梗阻伴 Dietl 危机行肾盂成形术的患者,根据肾图表现进行分类。组 1 患者诊断为皮质滞留,组 2 患者初始扫描表现为梗阻(T1/2 大于 20 分钟且无皮质滞留),组 3 患者初始扫描表现为无诊断价值(T1/2 小于 20 分钟且无皮质滞留)。分析每组患者的肾图参数。

结果

共 59 例患者符合研究纳入标准。组 1 的 13 例患者在肾盂成形术后功能恢复最显著(平均分肾功能改变 13.59%)。组 2 的 38 例患者平均分肾功能改变 43.06%(20%至 54.6%),术前 T1/2 平均值为 64.31 分钟。根据后续诊断性扫描(4 例)或与进一步症状发作相关的其他影像学检查中积水加重(4 例),对组 3 的 8 例患者均进行了肾盂成形术。组 3 初始肾图表现包括双相曲线、15 分钟直立位时清除率降低或有症状而无梗阻性引流。

结论

利尿剂肾图的解读需要综合多个参数,因为 Dietl 危机患者的肾图表现可能因肾盂输尿管连接部梗阻的间歇性而存在差异。皮质滞留是急性肾盂输尿管连接部梗阻的特定且特征性表现。通过对这些参数的适当评估,可以可靠地诊断梗阻,并选择合适的手术患者。

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