Lam Wayne, Fernando Archana, Issa Rami, Heenan Sue, Sandhu Sarb, Le Roux Pieter, Anderson Christopher
Department of Urology, St George's Hospital, London, United Kingdom; Department of Urology, Kingston Hospital, Kingston-upon-Thames, United Kingdom; Department of Urology, Epsom and St Helier University Hospitals, Surrey, United Kingdom.
Department of Urology, St George's Hospital, London, United Kingdom.
Urology. 2015 Jan;85(1):246-51. doi: 10.1016/j.urology.2014.09.033.
To determine if routine follow-up diuresis renography is indicated in all adult patients after pyeloplasty for ureteropelvic junction obstruction (UPJO).
A multicenter retrospective analysis was conducted in adults who underwent pyeloplasty for symptomatic UPJO between January 2002 and August 2012. Patients with unilateral UPJO demonstrated on diuresis renography, treated with pyeloplasty, and aged >18 years at time of surgery were included in the study. Patients with contralateral renal abnormalities, genitourinary anomalies, and those who declined renography during follow-up were excluded. All eligible patients underwent diuresis renography approximately 3 months postoperatively. Minimal follow-up was 12 months. Patients were divided into 2 groups: patients with persistent pain at 3 months after pyeloplasty and patients who became asymptomatic. Treatment failures in each cohort were identified. Comparisons were performed using the Fisher exact test.
A total of 100 pyeloplasties were performed. Of them, 90 were eligible for the study. Mean age was 40 years. Mean follow-up was 21 months. Seventy-three patients (81.1%) became pain free after pyeloplasty. One patient (1.4%) had worsening of differential renal function despite unobstructed drainage on diuresis renogram. None of the patients in the asymptomatic cohort was identified to have unequivocal drainage obstruction on postoperative renogram. Seventeen patients (18.9%) remained symptomatic with pain at 3 months after pyeloplasty; 3 (17.6%) of those patients with loin pain after pyeloplasty were confirmed to have persistent obstructed drainage postoperatively on diuresis renogram (P <.001). All 3 patients required insertion of ureteric stents and/or revision surgery (P <.007).
In our series, adult patients who became pain free after unilateral pyeloplasty for UPJO did not have persistent obstruction of renal drainage on renography. Routine diuresis renogram to assess drainage and differential renal function in patients who become pain free after pyeloplasty for UPJO may not be necessary. If objective evidence of postoperative outcome is required, then a single renogram at 3 months is recommended.
确定对于所有因肾盂输尿管连接部梗阻(UPJO)接受肾盂成形术的成年患者,常规的随访利尿肾图检查是否必要。
对2002年1月至2012年8月间因有症状的UPJO接受肾盂成形术的成年患者进行多中心回顾性分析。纳入标准为:经利尿肾图证实为单侧UPJO、接受肾盂成形术治疗且手术时年龄大于18岁的患者。排除对侧肾脏异常、泌尿生殖系统畸形以及随访期间拒绝行肾图检查的患者。所有符合条件的患者在术后约3个月接受利尿肾图检查。最短随访时间为12个月。患者分为两组:肾盂成形术后3个月仍有持续性疼痛的患者和无症状的患者。确定每组中的治疗失败病例。采用Fisher精确检验进行比较。
共进行了100例肾盂成形术。其中90例符合研究条件。平均年龄为40岁。平均随访时间为21个月。73例患者(81.1%)肾盂成形术后疼痛消失。1例患者(1.4%)尽管利尿肾图显示引流通畅,但肾功能差异仍有恶化。无症状组中无一例患者术后肾图显示明确的引流梗阻。17例患者(18.9%)在肾盂成形术后3个月仍有疼痛症状;其中3例(17.6%)肾盂成形术后腰痛患者经利尿肾图证实术后存在持续性引流梗阻(P<.001)。所有3例患者均需要置入输尿管支架和/或进行翻修手术(P<.007)。
在我们的系列研究中,因UPJO接受单侧肾盂成形术后疼痛消失的成年患者肾图检查未发现肾脏引流持续梗阻。对于因UPJO接受肾盂成形术后疼痛消失的患者,常规行利尿肾图以评估引流和肾功能差异可能没有必要。如果需要术后结果的客观证据,建议在3个月时进行一次肾图检查。