Waller Brittany, Haber Richard M
Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Arch Dermatol. 2012 Sep;148(9):1037-9. doi: 10.1001/archdermatol.2012.1625.
Transverse nasal crease is an uncommonly reported entity. It likely represents an embryologic fault line. Transverse nasal milia have also been reported in the same location, both as an isolated finding and in a transverse nasal crease. This observation suggests they are variants of the same entity.
Two cases, one of transverse nasal crease with milia and one of transverse nasal milia in the absence of a crease, are reported. A review of the literature on these rarely reported conditions was performed.
It is important for clinicians to be aware of transverse nasal creases, since they may be encountered in a dermatologic practice. Transverse nasal creases, milia in transverse nasal creases, transverse nasal milia, and transverse nasal comedones in the absence of a transverse nasal crease are likely variants of the same entity. They most probably occur because the triangular cartilage and the alar cartilage attach in a linear fashion at the junction of the middle and lower third of the nose. This produces a potential embryonic fault line in which retention cysts presenting as milia and comedones can occur. These clinical presentations merit attention because they are likely much more common than reported.
横向鼻褶是一种报道较少见的情况。它可能代表一条胚胎发育的断层线。横向鼻粟丘疹也在同一位置被报道过，既作为一种孤立的表现，也出现在横向鼻褶中。这一观察结果表明它们是同一实体的变体。
报告了两例病例，一例为伴有粟丘疹的横向鼻褶，另一例为无鼻褶的横向鼻粟丘疹。对这些罕见情况的文献进行了回顾。
临床医生了解横向鼻褶很重要，因为在皮肤科实践中可能会遇到。横向鼻褶、横向鼻褶中的粟丘疹、横向鼻粟丘疹以及无横向鼻褶时的横向鼻粉刺很可能是同一实体的变体。它们最有可能是因为三角形软骨和鼻翼软骨在鼻中下三分之一交界处呈线性附着而产生的。这产生了一条潜在的胚胎断层线，在其中可能出现表现为粟丘疹和粉刺的潴留囊肿。这些临床表现值得关注，因为它们可能比报道的更为常见。
