Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Curr Hypertens Rep. 2012 Dec;14(6):591-5. doi: 10.1007/s11906-012-0308-1.
Although the epidemic of childhood obesity in the developed world has resulted in more children being diagnosed with primary hypertension, renovascular disease remains an important consideration. The reason for investigation is to try and delineate if renovascular disease is present, as there is the potential to treat this group of patients. Those patients are usually identified by poor blood pressure control, despite the use of multiple anti-hypertensive medications or having known associated syndromes. Although advances in Doppler renal ultrasonography, computed tomography angiography (CTA) and magnetic resonance angiography (MRA) have occurred over the last decade, digital subtraction angiography remains the gold standard investigation, and offers a possible therapeutic intervention at the same time.
尽管发达国家儿童肥胖症的流行导致更多的儿童被诊断为原发性高血压,但肾血管性疾病仍然是一个重要的考虑因素。进行调查的原因是试图确定是否存在肾血管性疾病,因为有可能治疗这组患者。这些患者通常通过血压控制不佳来识别,尽管使用了多种抗高血压药物或有已知的相关综合征。尽管过去十年中多普勒肾超声、计算机断层血管造影 (CTA) 和磁共振血管造影 (MRA) 都取得了进展,但数字减影血管造影仍然是金标准检查,并同时提供了可能的治疗干预。