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登山者高密度脂蛋白显著增加。

Marked increase in high density lipoproteins in mountaineers.

作者信息

Nestel P J, Podkolinski M, Fidge N H

出版信息

Atherosclerosis. 1979 Oct;34(2):193-6. doi: 10.1016/0021-9150(79)90139-4.

DOI:10.1016/0021-9150(79)90139-4
PMID:229872
Abstract

Apoprotein-AI concentrations were measured in whole blood in 13 male mountaineers before, during and after a strenuous climb of 8 weeks' duration. The AI concentration almost doubled in 3 weeks and remained elevated at that level for the full period of the climb. This study demonstrates the rapid rate at which high density lipoproteins can rise and the very high levels (148 +/- 29 mg/dl in whole blood) that can be reached. The rise can be attributed at least in part to exercise though other factors such as exposure to cold, hypoxia and mental stress might also have contributed.

摘要

在13名男性登山运动员进行为期8周的艰苦攀登之前、期间和之后,测量了他们全血中的载脂蛋白A-I浓度。载脂蛋白A-I浓度在3周内几乎翻倍,并在整个攀登期间一直维持在该升高水平。这项研究证明了高密度脂蛋白能够快速升高,并且能够达到非常高的水平(全血中为148±29毫克/分升)。这种升高至少部分归因于运动,不过其他因素,如暴露于寒冷、缺氧和精神压力等,可能也起到了一定作用。

相似文献

1
Marked increase in high density lipoproteins in mountaineers.登山者高密度脂蛋白显著增加。
Atherosclerosis. 1979 Oct;34(2):193-6. doi: 10.1016/0021-9150(79)90139-4.
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引用本文的文献

1
High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice.高密度脂蛋白通过调节小鼠细胞呼吸维持骨骼肌功能。
Circulation. 2013 Nov 26;128(22):2364-71. doi: 10.1161/CIRCULATIONAHA.113.001551. Epub 2013 Oct 29.
2
[The apolipoproteins in man ].[人类中的载脂蛋白]
Klin Wochenschr. 1982 Jul 1;60(13):673-49. doi: 10.1007/BF01716796.
3
Marked elevation of HDL-cholesterol in cold-adapted golden hamsters.冷适应金黄地鼠中高密度脂蛋白胆固醇显著升高。
Experientia. 1986 Feb 15;42(2):153-5. doi: 10.1007/BF01952442.
4
Changes in plasma lipids and lipoprotein cholesterol during a high altitude mountaineering expedition (4800 m).
Eur J Appl Physiol Occup Physiol. 1988;57(6):740-5. doi: 10.1007/BF01075997.