冷适应金黄地鼠中高密度脂蛋白胆固醇显著升高。
Marked elevation of HDL-cholesterol in cold-adapted golden hamsters.
作者信息
Sicart R, Sablé-Amplis R, Bluthé E
出版信息
Experientia. 1986 Feb 15;42(2):153-5. doi: 10.1007/BF01952442.
PMID:3456307
Abstract
Golden hamsters with spontaneous hypercholesterolemia at 22 degrees C developed a further increase in plasma cholesterol when they were maintained at 6 degrees C. This hypercholesterolemia was associated with a redistribution of plasma cholesterol between VLDL and HDL. Plasma cholesterol transported in the VLDL decreased while cholesterol in the HDL increased by 45%. The LDL profile was not significantly modified.
摘要
在22摄氏度下患有自发性高胆固醇血症的金黄地鼠，当饲养在6摄氏度时，其血浆胆固醇会进一步升高。这种高胆固醇血症与血浆胆固醇在极低密度脂蛋白（VLDL）和高密度脂蛋白（HDL）之间的重新分布有关。VLDL中运输的血浆胆固醇减少，而HDL中的胆固醇增加了45%。低密度脂蛋白（LDL）的情况没有明显改变。
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