Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10633-7. doi: 10.1002/anie.201204015. Epub 2012 Sep 17.
Highly reactive gold vinylidene species are used for intermolecular C(sp(3))-H insertions into unactivated alkanes (see scheme). In addition, they can be regarded as synthons for alkylidene carbenes. Initiated by cyclopropanation of the vinylidene species/alkylidene carbenoide, cyclobutene derivatives are formed in a diastereoselective fashion by a ring-enlargement cascade in only one step.
高活性金 vinylidene 物种用于将分子间 C(sp(3))-H 插入到非活化的烷烃中（见方案）。此外，它们可以被视为亚烷基卡宾的前体。通过 vinylidene 物种/亚烷基碳烯化物的环丙烷化引发，通过一步中环扩大级联反应以非对映选择性方式形成环丁烯衍生物。
