Vicario Augusto, Del Sueldo Mildren, Fernández Ruth A, Enders Julio, Zilberman Judith, Cerezo Gustavo H
Department of Internal Medicine, Cardiovascular Division, Hospital Español de Buenos Aires, Argentina ; Argentine Federation of Cardiology (AFC), Buenos Aires, Argentina ; Research Group, Human Health Commission, CERTUS Foundation, Villa María, Córdoba, Argentina.
Int J Hypertens. 2012;2012:783696. doi: 10.1155/2012/783696. Epub 2012 Sep 4.
We conducted an epidemiological approach to identify the negative impact of the vascular risk factors (such as hypertension, diabetes and hypercholesterolemia) over cognition. The interesting aspect of this study was that the survey was conducted in all age groups through a voluntary call (n = 1365; ≥18 years old, both sexes; age 49 ± 15 y, female 75.7%). Thus, we demonstrated that the use of a Minimum Cognitive Examination (MCE), a brief, simple, and easy managed neuropsychological evaluation, detected a greater number of people with cognitive decline surpassing to the Minimal Mental Statement Examination alone (14.5% of the participants showed MMSE ≤24, 34,6% showed dys-executive function, and 45,8% memory impairment. Out of the 4 studied RF, the only one that was not related to cognitive impairment was dyslipemia. Finally, we noted the importance of cognitive state early detection in all age groups, even in the youngest group. Acting in the middle of the life stages, we can prevent or delay the onset of a disease in adults, nowadays incurable: dementia.
我们采用流行病学方法来确定血管危险因素（如高血压、糖尿病和高胆固醇血症）对认知的负面影响。这项研究的有趣之处在于，通过自愿报名电话调查了所有年龄组（n = 1365；≥18岁，男女不限；年龄49±15岁，女性占75.7%）。因此，我们证明，使用简易认知检查（MCE），一种简短、简单且易于管理的神经心理学评估方法，检测出认知功能下降的人数比仅使用简易精神状态检查表更多（14.5%的参与者MMSE≤24，34.6%表现出执行功能障碍，45.8%存在记忆障碍。在研究的4种危险因素中，唯一与认知障碍无关的是血脂异常。最后，我们指出了在所有年龄组中早期发现认知状态的重要性，即使是最年轻的组。在生命阶段的中期采取行动，我们可以预防或延缓成年人中目前无法治愈的疾病——痴呆症的发病。
