Department of Physical Education, Busan National University of Education, Busan, South Korea.
Metab Syndr Relat Disord. 2012 Dec;10(6):452-7. doi: 10.1089/met.2012.0036. Epub 2012 Sep 18.
The percentage of obese postmenopausal women with metabolic syndrome is rising, and physical factors associated with the metabolic syndrome prevalence or incidence are also rising, including high body mass index (BMI), visceral fat area (VFA), low plasma sex hormone-binding globulin (SHBG) levels, and low cardiorespiratory fitness. Therefore, we investigated the influence of aerobic exercise on SHBG, body fat index (BFI), and metabolic syndrome factors in obese postmenopausal Korean women.
Thirty healthy postmenopausal, women aged 53.46 ± 2.4 years and with over 32% body fat, were randomly assigned to an aerobic exercise group (EX; n=15) or to a "nonexercise" control (Con; n=15) group. The primary outcome measurements were serum SHBG, lipid profiles, insulin levels, and metabolic syndrome factors. Secondary outcome measurements were body composition, VFA, blood pressure (BP), and homeostasis model assessment of insulin resistance (HOMA-IR).
Posttraining body weight and BFI (P<0.05), total cholesterol, glucose, and insulin levels (P<0.01), BP, and HOMA-IR (P<0.001) decreased, whereas SHBG (P<0.001) and metabolic syndrome factors (P<0.01) improved in the exercise group but not in the control group. SHBG levels also showed a significant positive correlation with high-density lipoprotein cholesterol (HDL-C) and significant negative correlations withglucose, diastolic blood pressure, fat mass, BMI, and percent body fat (P<0.05).
Our findings indicate that aerobic exercise improves body composition, SHBG, insulin levels, and metabolic syndrome factors. These findings suggest that in obesepostmenopausal Korean women, 16 weeks of aerobic exercise is effective for preventing the metabolic syndrome caused by obesity.
患有代谢综合征的肥胖绝经后妇女的比例正在上升，与代谢综合征患病率或发病率相关的身体因素也在上升，包括高体重指数（BMI）、内脏脂肪面积（VFA）、低血浆性激素结合球蛋白（SHBG）水平和低心肺健康水平。因此，我们研究了有氧运动对肥胖绝经后韩国女性 SHBG、体脂指数（BFI）和代谢综合征因素的影响。
30 名健康的绝经后女性，年龄 53.46±2.4 岁，体脂超过 32%，随机分为有氧运动组（EX；n=15）或“非运动”对照组（Con；n=15）。主要观察指标为血清 SHBG、血脂谱、胰岛素水平和代谢综合征因素。次要观察指标为身体成分、VFA、血压（BP）和胰岛素抵抗的稳态模型评估（HOMA-IR）。
训练后体重和 BFI（P<0.05）、总胆固醇、葡萄糖和胰岛素水平（P<0.01）、BP 和 HOMA-IR（P<0.001）降低，而 SHBG（P<0.001）和代谢综合征因素（P<0.01）在运动组改善，但在对照组没有改善。SHBG 水平与高密度脂蛋白胆固醇（HDL-C）呈显著正相关，与葡萄糖、舒张压、脂肪量、BMI 和体脂百分比呈显著负相关（P<0.05）。
我们的发现表明有氧运动改善了身体成分、SHBG、胰岛素水平和代谢综合征因素。这些发现表明，在肥胖的绝经后韩国女性中，16 周的有氧运动对预防肥胖引起的代谢综合征是有效的。
