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甲状腺手术中喉返神经损伤:综述

Recurrent laryngeal nerve injury in thyroid surgery: a review.

作者信息

Hayward Nathan James, Grodski Simon, Yeung Meei, Johnson William R, Serpell Jonathan

机构信息

Department of Breast, Endocrine and General Surgery, The Alfred Hospital,55 Commercial Road, Prahran, Vic.3181, Australia.

出版信息

ANZ J Surg. 2013 Jan;83(1-2):15-21. doi: 10.1111/j.1445-2197.2012.06247.x. Epub 2012 Sep 18.

Abstract

Recurrent laryngeal nerve palsy (RLNP) is an important and potentially catastrophic complication of thyroid surgery. Permanent RLNP occurs in 0.3-3% of cases, with transient palsies in 5-8%. A literature review and analysis of recent data regarding RLNP in thyroid surgery was performed, with particular focus on the identification of high-risk patients, the role of intraoperative identification and dissection of the nerve, and the role of intraoperative neuromonitoring (IONM) and optimal perioperative nerve assessment. In conjunction with the review, data from the Monash University/Alfred Hospital Endocrine Surgery Unit between January 2007 and October 2011 were retrospectively analysed, including 3736 consecutive nerves at risk (NAR). The current literature and our data confirm that patients undergoing re-operative thyroid surgery and thyroid surgery for malignancies are at increased risk of RLNP. Intraoperative visualization and capsular dissection of the RLN remain the gold standard for intraoperative care during thyroid surgery for reducing RLNP risk. IONM should not be used as the sole mechanism for identifying and preserving the nerve, although it can be used to aid in the identification and dissection of the nerve, and may aid in nerve protection in high-risk cases including cancer surgery and re-operative surgery.

摘要

喉返神经麻痹(RLNP)是甲状腺手术一种重要且可能引发灾难性后果的并发症。永久性RLNP发生率为0.3% - 3%,暂时性麻痹发生率为5% - 8%。我们进行了一项关于甲状腺手术中RLNP的文献综述及近期数据分析,特别关注高危患者的识别、术中神经识别与解剖的作用、术中神经监测(IONM)的作用以及围手术期最佳神经评估。结合该综述,我们对莫纳什大学/阿尔弗雷德医院内分泌外科2007年1月至2011年10月期间的数据进行了回顾性分析,包括3736条连续的有风险神经(NAR)。当前文献及我们的数据证实,再次接受甲状腺手术以及因恶性肿瘤接受甲状腺手术的患者发生RLNP的风险增加。在甲状腺手术中,术中直视喉返神经并进行包膜下解剖仍是降低RLNP风险的术中护理金标准。IONM不应作为识别和保留神经的唯一手段,尽管它可用于辅助神经识别与解剖,并且在包括癌症手术和再次手术等高风险病例中可能有助于神经保护。

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