Firth Alison Y, Stevenson Clare
Binocul Vis Strabolog Q Simms Romano. 2012;27(3):187-94.
There are conflicting reports concerning the relationship between depth of suppression and level of amblyopia in strabismics. Little attention has been given to anisometropes. This study examines the density of suppression in anisometropic amblyopes, with or without microtropia, and investigates whether there is a relationship with level of amblyopia.
Patients with anisometropia (defined as a difference of 1D or 0.5 D cyl), binocular single vision and a difference in corrected visual acuity of at least 0.1 logMAR between eyes were recalled. The degree of amblyopia was expressed as the interocular difference using the Bailey-Lovie logMAR chart. Stereoacuity (Titmus test), binocular alignment and fixation were recorded. The depth of suppression was measured using the neutral density filter bar together with the Worth four dot test at 4.5m (subtending an angle of 0.5 degrees). Best spherical equivalent (BSE) was calculated to represent anisometropia.
Thirteen participants aged 8.3 years to 12.1 years (mean 9.7 years) completed the study. No significant correlation was present (r=0.10, p=0.74) between the depth of suppression and degree of amblyopia. However, there was a correlation between depth of suppression and level of stereoacuity (r=0.59, p=0.03). Six participants had microtropia and showed stronger suppression (p=0.03) and worse stereoacuity (p=0.001) than the pure anisometropes.
No evidence was found of a relationship between density of suppression and amblyopia in this cohort of anisometropic amblyopes.
关于斜视性弱视患者抑制深度与弱视程度之间的关系，存在相互矛盾的报道。而对于屈光参差性弱视患者，关注较少。本研究检测了伴有或不伴有微小斜视的屈光参差性弱视患者的抑制密度，并探究其与弱视程度之间是否存在关联。
召回屈光参差（定义为球镜相差1D或柱镜相差0.5D）、双眼单视且双眼矫正视力相差至少0.1 logMAR的患者。使用贝利-洛维对数视力表，将弱视程度表示为两眼间差异。记录立体视锐度（Titmus测试）、双眼眼位和注视情况。在4.5米处使用中性密度滤光条结合沃思四点试验测量抑制深度（视角为0.5度）。计算最佳球镜等效度数（BSE）以表示屈光参差。
13名年龄在8.3岁至12.1岁（平均9.7岁）的参与者完成了研究。抑制深度与弱视程度之间无显著相关性（r = 0.10，p = 0.74）。然而，抑制深度与立体视锐度水平之间存在相关性（r = 0.59，p = 0.03）。6名患有微小斜视的参与者比单纯屈光参差患者表现出更强的抑制（p = 0.03）和更差的立体视锐度（p = 0.001）。
在该组屈光参差性弱视患者中，未发现抑制密度与弱视之间存在关联的证据。
