Department of Neurology, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.
J Clin Neurosci. 2012 Dec;19(12):1728-30. doi: 10.1016/j.jocn.2012.01.037. Epub 2012 Sep 16.
In the wake of the worldwide H1N1 pandemic, there has been evidence that the H1N1 influenza virus is associated with neurological complications. This is the first report describing status epilepticus in an adult patient with H1N1 virus infection, to our knowledge. This patient had no prior history of epilepsy and presented with complex partial status epilepticus. This was further illustrated on electroencephalographs and MRI brain changes that corresponded with the patient's clinical state and which subsequently resolved on follow-up. Although uncommon, H1N1 infections may result in central nervous system complications in adults and it is crucial to treat such patients with urgency.
在全球 H1N1 大流行之后,有证据表明 H1N1 流感病毒与神经系统并发症有关。据我们所知,这是首例描述成人 H1N1 病毒感染后癫痫持续状态的报告。该患者既往无癫痫病史,表现为复杂部分性癫痫持续状态。脑电图和 MRI 脑改变进一步说明了这一点,这些改变与患者的临床状态相对应,并在随访中得到了缓解。虽然不常见,但 H1N1 感染可能导致成人中枢神经系统并发症,因此急需对这些患者进行治疗。