Gezer M, Tasci I, Demir O, Acikel C, Cakar M, Saglam K, Kutsi Kabul H, Fatih Bulucu M, Acar R, Ozturk K, Inanc Dogan M, Koc B
Department of Internal Medicine, Gulhane School of Medicine, Ankara, Turkey.
Int Angiol. 2012 Oct;31(5):454-61.
Peripheral arterial disease (PAD) is a less known condition in the practice of internal medicine, mostly due to lack of specific symptoms and low rates of physician awareness. However, cardiovascular disease (CVD) incidence is not significantly different among patients with symptomatic or asymptomatic disease. Ankle brachial index (ABI) measurement is an easy and cost-effective tool for the diagnosis of PAD. In the present study, frequency of low ABI and associated factors were investigated in the setting of internal medicine practice.
Patients over 70 years of age and patients between 50 and 69 years with CVD or at least one atherothrombosis risk factor were included in the study. ABI was determined with handheld Doppler. Measurements were determined for both lower extremities. Lower of the right or left ABIs was taken as the final value. Low ABI was defined as ≤0.9.
A total of 303 subjects between 50 and 83 years of age were enrolled (female/male: 186/117). Mean ABI was 1.14±0.15. A low ABI was detected in 15 cases (4.95%). Prevalence was 7% in females and 1.7% in males (P=0.039). Low ABI value was not associated with any of the demographic parameters, presence of major risk factors or basic laboratory values. A high ABI was found by 5.6%.
In the present study, frequency of PAD as determined by ABI was found lower than those reported previously in most European countries. Nonetheless, our results showed that PAD affects at least 1 in 20 outpatients in the practice of internal medicine.
外周动脉疾病（PAD）在内科实践中是一种鲜为人知的病症，主要是因为缺乏特异性症状且医生认知率较低。然而，有症状或无症状疾病患者的心血管疾病（CVD）发病率并无显著差异。踝臂指数（ABI）测量是诊断PAD的一种简便且经济高效的工具。在本研究中，我们在内科实践环境中调查了低ABI的发生率及相关因素。
本研究纳入了70岁以上的患者以及50至69岁患有CVD或至少有一个动脉粥样硬化血栓形成风险因素的患者。使用手持式多普勒仪测定ABI。对双下肢进行测量。取左右ABI中的较低值作为最终值。低ABI定义为≤0.9。
共纳入了303名年龄在50至83岁之间的受试者（女性/男性：186/117）。平均ABI为1.14±0.15。在15例患者（4.95%）中检测到低ABI。女性患病率为7%，男性为1.7%（P = 0.039）。低ABI值与任何人口统计学参数、主要风险因素的存在或基本实验室值均无关联。发现高ABI的比例为5.6%。
在本研究中，通过ABI测定的PAD发生率低于大多数欧洲国家先前报道的水平。尽管如此，我们的结果表明，在内科门诊患者中，至少每20人中有1人受PAD影响。
