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[食管癌微创食管切除术:160例临床分析]

[Minimally invasive esophagectomy for esophageal carcinoma: clinical analysis of 160 cases].

作者信息

Zhang Zhen-ming, Wang Yun, Gao Yong-shan, Song Yu, Ma Lin

机构信息

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2012 Sep;15(9):934-7.

Abstract

OBJECTIVE

To explore the feasibility, safety and clinical application value of minimally invasive esophagectomy (MIE).

METHODS

Clinical data of 160 patients undergoing minimally invasive approach in the West China Hospital of Sichuan University between February 2008 and December 2011 were analyzed retrospectively.

RESULTS

There were 140 males and 20 females with a mean age of 59.6 years. Approaches to esophagectomy were thoracoscopic and laparoscopic esophagectomy (n=139), thoracoscopic and mediastinoscopic esophagectomy (n=3), laparoscopic-assisted Ivor Lewis resection (n=15), thoraco-laparoscopic Ivor Lewis resection (n=3). The mean operative time was 364 (range 230-780) min and the mean blood loss was 286.2 (range 20 to 4000) ml. The tumor free resection margins (R0) were completely in 152 cases (95.0%). The mean lymph node harvested was 19.4 (range 6-39). There were 11 (6.9%) cases converted to open operation including 9 thoracotomy and 2 laparotomy. The intraoperative complication rate was 11.3% (18/160). The average length of intensive care unit (ICU) stay was 22.1(range 0 to 430) h and the average length of postoperative hospital stay was 13.1 (range 7-93 d). Postoperative complication occurred in 34.4% of patients. The 30-day mortality was 1.2% (2/160) and the overall mortality was 2.5% (4/160).

CONCLUSION

MIE is technically feasible and safe for the treatment of esophageal carcinoma, which provides good or even better outcomes than open approach.

摘要

目的

探讨微创食管切除术(MIE)的可行性、安全性及临床应用价值。

方法

回顾性分析2008年2月至2011年12月在四川大学华西医院接受微创治疗的160例患者的临床资料。

结果

男性140例,女性20例,平均年龄59.6岁。食管切除方法包括胸腔镜和腹腔镜食管切除术(n = 139)、胸腔镜和纵隔镜食管切除术(n = 3)、腹腔镜辅助Ivor Lewis切除术(n = 15)、胸腹腔镜Ivor Lewis切除术(n = 3)。平均手术时间为364(230 - 780)分钟,平均失血量为286.2(20 - 4000)毫升。152例(95.0%)患者实现肿瘤切缘阴性(R0)。平均清扫淋巴结数为19.4(6 - 39)枚。11例(6.9%)患者中转开腹手术,其中9例开胸,2例开腹。术中并发症发生率为11.3%(18/160)。重症监护病房(ICU)平均住院时间为22.1(0 - 430)小时,术后平均住院时间为13.1(7 - 93)天。34.4%的患者发生术后并发症。30天死亡率为1.2%(2/160),总死亡率为2.5%(4/160)。

结论

MIE治疗食管癌在技术上可行且安全,其疗效优于或甚至等同于开放手术。

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