Yu Yue, Han Yun
Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China.
Evid Based Complement Alternat Med. 2022 Jun 26;2022:4507696. doi: 10.1155/2022/4507696. eCollection 2022.
To investigate the clinical effect and postoperative pain of laparo-thoracoscopic esophagectomy in patients with esophageal cancer.
A total of 90 patients with esophageal cancer who were admitted and treated in our hospital from August 2020 to November 2021 were randomly selected as the research subjects for prospective analysis, and the patients were assigned to the control group and the experimental group according to the time of admission equally, with 45 cases in each group. Patients in the control group underwent conventional open surgery, and those in the experimental group underwent laparo-thoracoscopic esophagectomy. Then, operation-related indicators, postoperative pain, inflammatory factors, and complications were compared between the two groups.
The operation time, intraoperative blood loss, postoperative drainage, and postoperative length of stays of the experimental group were significantly shorter or less than those of the control group ( < 0.05); there was no significant difference in the number of lymph nodes dissected between the two groups ( > 0.05). The number of patients with moderate and severe pain in the experimental group was significantly smaller than that in the control group, and the number of patients with mild pain was significantly larger than that in the control group ( < 0.05). The level of inflammatory factors (TNF-, IL-6, IL-8, and IL-10) was significantly lower than that in the control group ( < 0.05); the incidence of surgical complications in the experimental group was significantly lower than that in the control group ( < 0.05).
Laparo-thoracoscopic esophagectomy can significantly improve the clinical effect in patients with esophageal cancer. Thoracic-laparoscopic esophagectomy can significantly improve the clinical results of patients with esophageal cancer. With better performance in surgery-related indicators, lower inflammatory factor levels and postoperative pain, and fewer postoperative complications, it will speed up patients' recovery and is worthy of clinical promotion and application.
探讨腹腔镜辅助胸腔镜食管癌切除术治疗食管癌患者的临床疗效及术后疼痛情况。
选取2020年8月至2021年11月在我院收治并接受治疗的90例食管癌患者作为研究对象进行前瞻性分析，根据入院时间将患者平均分为对照组和试验组，每组45例。对照组患者接受传统开放手术，试验组患者接受腹腔镜辅助胸腔镜食管癌切除术。然后，比较两组患者的手术相关指标、术后疼痛、炎症因子及并发症情况。
试验组的手术时间、术中出血量、术后引流量及术后住院时间均显著短于或少于对照组（P<0.05）；两组清扫淋巴结数目差异无统计学意义（P>0.05）。试验组中、重度疼痛患者数量显著少于对照组，轻度疼痛患者数量显著多于对照组（P<0.05）。试验组炎症因子（TNF-α、IL-6、IL-8和IL-10）水平显著低于对照组（P<0.05）；试验组手术并发症发生率显著低于对照组（P<0.05）。
腹腔镜辅助胸腔镜食管癌切除术可显著提高食管癌患者的临床疗效。胸腔镜辅助腹腔镜食管癌切除术可显著改善食管癌患者的临床效果。在手术相关指标方面表现更佳，炎症因子水平及术后疼痛更低，术后并发症更少，能加快患者康复，值得临床推广应用。
