Materials and Science Engineering, Graduate School of Pure and Applied Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan.
Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10537-41. doi: 10.1002/anie.201204139. Epub 2012 Sep 18.
Caught in a web: Photo-cross-linkable temperature-responsive polymer-based nanofiber webs have been synthesized that have the ability to capture, encapsulate, and release cells by dynamically transforming the fibrous structure into hydrogel-like structures by wrapping, swelling, and deswelling processes in response to external temperature changes (see picture).
已合成了可光交联的温敏聚合物纳米纤维网,这些纤维网具有通过动态转变纤维结构为水凝胶状结构的能力,通过包封、溶胀和收缩过程对外界温度变化做出响应,从而捕获、封装和释放细胞(见图)。