University of Nova Gorica (UNG), PO Box 301, Rožna Dolina (Nova Gorica) 5000, Slovenia.
J Cell Biochem. 2013 Mar;114(3):510-3. doi: 10.1002/jcb.24393.
Peptide signal sequences attached to or embedded into a core protein sequence control its cellular localization and several post-translational modifications. However, misleading or cumbersome results may be generated when expressing recombinant proteins with modified signal peptides or single domains of larger proteins.
肽信号序列附着或嵌入到核心蛋白序列上，控制其细胞定位和几种翻译后修饰。然而，当用修饰的信号肽或较大蛋白质的单个结构域表达重组蛋白时，可能会产生误导或繁琐的结果。
