Taghavi Zenouz Ali, Mehdipour Masoumeh, Attaran Rana, Bahramian Ayla, Emamverdi Zadeh Paria
Associate Professor, Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
J Dent Res Dent Clin Dent Prospects. 2012 Winter;6(1):29-32. doi: 10.5681/joddd.2012.007. Epub 2012 Mar 13.
Lichenoid reactions represent a family of lesions with different etiologic factors and a common clinical and histologic ap-pearance. Lichen planus is included with lichenoid reactions and is a relatively common chronic mucocutaneous disorder. The most important complication of lichenoid reactions is the possibility of malignant transformation. That is why it has been considered a precancerous condition. Although the malignant transformation rate varies widely in the literature, from 0.4 to 6.5 percent, in most studies it does not exceed 1%. The aim of this paper is to report a rare case of squamous cell car-cinoma (SCC) arising within an oral lichenoid lesion in a 17-year-old woman, where SCC is very uncommon. The patient did not have any risk factors and was healthy. The lesion was located on the border of the tongue. In view of thecommon occurrence of OLP (oral lichen planus) and the unresolved issues regarding its premalignant potential, this case report illus-trates the need for histologic confirmation and a close follow-up of clinical lesions with lichenoid features.
苔藓样反应是一组具有不同病因因素但临床和组织学表现相似的病变。扁平苔藓属于苔藓样反应，是一种相对常见的慢性黏膜皮肤疾病。苔藓样反应最重要的并发症是发生恶性转化的可能性。这就是为什么它被认为是一种癌前状态。尽管文献中报道的恶性转化率差异很大，从0.4%到6.5%，但在大多数研究中，该转化率不超过1%。本文旨在报告一例罕见的17岁女性口腔苔藓样病变内发生鳞状细胞癌（SCC）的病例，SCC在该年龄段非常罕见。该患者没有任何危险因素，身体健康。病变位于舌缘。鉴于口腔扁平苔藓（OLP）的常见性及其潜在恶性病变相关问题尚未解决，本病例报告说明了对具有苔藓样特征的临床病变进行组织学确诊和密切随访的必要性。
