Ishizawa Michi, Matsumoto Sonoko, Tajima Keiko, Konishi Ruriko, Itsuhata Hiromasa M
Department of Anesthesiology, Juntendo Tokyo Koto Geriatric Medical Center Tokyo 136-0075.
Masui. 2012 Aug;61(8):869-71.
A 51-year-old woman was scheduled for emergency enterectomy and vascular repair under general anesthesia for active bleeding from internal iliac artery caused by repeated radiotherapy for cervical cancer and subsequent hypovolemic shock. For the first two hours of operation, the blood loss exceeded 6,000 ml and the hemoglobin level decreased to a low of 3.8 g x dl(-1) despite administration of 38 units of packed red cells. Intraoperative blood salvage was used in order to minimize further loss of hemoglobin. Mild hypothermia technique was also introduced to prevent brain ischemia. Total bleeding volume was approximately 10,000 ml, and total transfused volume was 8,740 ml. No neurological deficit and no systemic infection were found during the postoperative course. Although clinical risks of cell salvage in patients undergoing surgery for malignant tumor remain controversial, we conclude intraoperative blood salvage using Cell Saver could be utilized as a life-saving means and mild hypothermia might have been efficacious for protecting the brain from ischemia in our case.
一名51岁女性计划在全身麻醉下进行急诊肠切除术和血管修复术,其因宫颈癌反复放疗导致髂内动脉活动性出血并继发低血容量性休克。手术的前两个小时,失血量超过6000毫升,尽管输注了38单位的浓缩红细胞,血红蛋白水平仍降至低至3.8克/分升。术中采用血液回收以尽量减少血红蛋白的进一步损失。还采用了轻度低温技术以预防脑缺血。总出血量约为10000毫升,总输血量为8740毫升。术后过程中未发现神经功能缺损和全身感染。尽管恶性肿瘤手术患者进行细胞回收的临床风险仍存在争议,但我们得出结论,在我们的病例中,使用血液回收机进行术中血液回收可作为一种挽救生命的手段,轻度低温可能对保护大脑免受缺血有效。