Oosthuizen J C, Kennedy S, Timon C
Department of Otorhinolaryngology, Head and Neck Surgery, The Royal Victoria Eye and Ear Hospital, Dublin, Republic of Ireland.
J Laryngol Otol. 2012 Oct;126(10):1069-72. doi: 10.1017/S0022215112001569.
Glomangiopericytoma is a rare sinonasal tumour of perivascular myoid phenotype, which accounts for less than 1 per cent of all sinonasal tumours.
Discussion of the clinical presentation, histopathological features and advances in the management of sinonasal and skull base glomangiopericytoma.
A 32-year-old woman presented with worsening nasal obstruction, anosmia, severe frontal headaches and right-sided proptosis. Radiographic and endoscopic examination revealed a right-sided, vascular mass involving the nasal cavity, paranasal sinuses and anterior skull base. Histopathological features were consistent with a glomangiopericytoma. Complete endoscopic resection with free margins was achieved.
Glomangiopericytomas are rare, vascular, sinonasal tumours. Successful management depends on complete resection, traditionally achieved via an open approach. However, recent advances in endoscopic surgical approaches have enabled complete endoscopic resection of these tumours, minimising morbidity and facilitating subsequent surveillance of the operative site.
血管外皮细胞瘤是一种罕见的具有血管周围肌样表型的鼻窦肿瘤，占所有鼻窦肿瘤的比例不到1%。
探讨鼻窦和颅底血管外皮细胞瘤的临床表现、组织病理学特征及治疗进展。
一名32岁女性出现鼻塞加重、嗅觉减退、严重额部头痛和右侧眼球突出。影像学和内镜检查显示右侧鼻腔、鼻窦和前颅底有一个血管性肿块。组织病理学特征符合血管外皮细胞瘤。通过内镜完整切除且切缘阴性。
血管外皮细胞瘤是罕见的鼻窦血管性肿瘤。成功的治疗取决于完整切除，传统上通过开放手术实现。然而，内镜手术方法的最新进展已能够通过内镜完整切除这些肿瘤，将发病率降至最低，并便于对手术部位进行后续监测。
