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血管外皮细胞瘤:一种罕见的鼻腔鼻窦肿瘤。

Glomangiopericytoma: A rare tumour of sinonasal cavity.

作者信息

Ghaloo Shayan Khalid, Dhanani Rahim, Pasha Hamdan Ahmed, Wasif Muhammad, Fatima Saira, Ikram Mubasher

机构信息

Aga Khan University Hospital, Karachi.

Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2020 Dec;70(12(B)):2469-2471. doi: 10.47391/JPMA.948.

DOI:10.47391/JPMA.948
PMID:33475567
Abstract

The history of glomangiopericytoma began in 1924 when it was initially diagnosed by Stout and Murray. It is a rare tumour of the respiratory mucosa, with a prevalence of less than 0.5% among all sinonasal tumours. Literature shows female predominance among patients who develop glomangiopericytoma. So far, no accurate aetiology has been discovered, but there are certain risk factors, including trauma, use of corticosteroids and high blood pressure, which are believed to cause glomangiopericytoma. Patients usually present with a history of epistaxis or nasal blockage, though symptoms can get worse if the tumour is not resected timely and can lead to visual disturbance, chronic sinusitis and headache. It has reddish polypoidal appearance on examination. The best modality for the treatment of glomangiopericytoma is endoscopic surgical resection via trans-nasal approach. We present the case of a 70-year-old man, with nasal blockage and epistaxis who underwent endoscopic sinus surgery for this condition.

摘要

血管外皮细胞瘤的历史始于1924年,当时它最初由斯托特和默里诊断出来。它是一种罕见的呼吸道黏膜肿瘤,在所有鼻窦肿瘤中的患病率不到0.5%。文献显示,患血管外皮细胞瘤的患者中女性占多数。到目前为止,尚未发现确切的病因,但存在某些危险因素,包括创伤、使用皮质类固醇和高血压,据信这些因素会导致血管外皮细胞瘤。患者通常有鼻出血或鼻塞病史,不过如果肿瘤未及时切除,症状会加重,并可能导致视力障碍、慢性鼻窦炎和头痛。检查时它呈红色息肉样外观。治疗血管外皮细胞瘤的最佳方式是经鼻内镜手术切除。我们报告一例70岁男性患者,因鼻塞和鼻出血接受了内镜鼻窦手术治疗此病症。

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Indian J Otolaryngol Head Neck Surg. 2025 Feb;77(2):1186-1191. doi: 10.1007/s12070-024-05280-9. Epub 2025 Jan 3.
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Clinical and histopathological findings of a rare sinonasal glomangiopericytoma.一例罕见鼻窦血管外皮细胞瘤的临床及组织病理学表现
Autops Case Rep. 2023 Apr 10;13:e2023424. doi: 10.4322/acr.2023.424. eCollection 2023.
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Sinonasal Glomangiopericytoma with Prolonged Postsurgical Follow-Up.
鼻窦血管外皮细胞瘤的长期术后随访
J Neurol Surg Rep. 2022 Jul 10;83(3):e87-e89. doi: 10.1055/a-1865-6801. eCollection 2022 Jul.
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A rare case of glomangiopericytoma in the nasal cavity: A case report in light of recent literature.鼻腔血管球性血管外皮细胞瘤1例罕见病例报告:结合近期文献的病例报告
Ann Med Surg (Lond). 2022 Apr 28;77:103685. doi: 10.1016/j.amsu.2022.103685. eCollection 2022 May.
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Molecular Biomarkers in Sinonasal Cancers: New Frontiers in Diagnosis and Treatment.鼻腔鼻窦肿瘤的分子标志物:诊断与治疗的新领域。
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Sinonasal Glomangiopericytoma: Review of Imaging Appearance and Clinical Management Update for a Rare Sinonasal Neoplasm.鼻窦血管外皮细胞瘤:一种罕见的鼻窦肿瘤的影像学表现和临床管理更新综述。
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