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[一名非洲 HIV 阳性患者中荚膜组织胞浆菌感染的麻风样皮肤表现]

[Leprosy-like cutaneous presentation of Histoplasma capsulatum infection in an African HIV+ patient].

作者信息

Scarlata Francesco, Imburgia Claudia, Trizzino Marcello, Titone Lucina

机构信息

Dipartimento di Scienze per la Promozione della Salute, Sezione di Malattie Infettive, Universita di Palermo, Palermo, Italy.

出版信息

Infez Med. 2012 Sep;20(3):211-3.

Abstract

Histoplasma capsulatum is an opportunistic dimorphic fungus responsible for most often self-limiting or flu-like infections but potentially lethal in immunocompromised hosts. Histoplasmosis is rare in Europe. We reported a case of disseminated histoplasmosis in an African HIV patient with a leprosy-like primary cutaneous presentation and involvement of lungs, brain, limphnodes and eye. The therapy with liposomial B amphotericin and itraconazole led to a prompt resolution of the symptoms.

摘要

荚膜组织胞浆菌是一种机会性双相真菌,常引起自限性或流感样感染,但在免疫功能低下的宿主中可能致命。组织胞浆菌病在欧洲很少见。我们报告了一例非洲艾滋病患者发生播散性组织胞浆菌病,其最初表现为麻风样皮肤损害,并累及肺、脑、淋巴结和眼。脂质体两性霉素B和伊曲康唑治疗使症状迅速缓解。

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