Scarlata Francesco, Imburgia Claudia, Trizzino Marcello, Titone Lucina
Dipartimento di Scienze per la Promozione della Salute, Sezione di Malattie Infettive, Universita di Palermo, Palermo, Italy.
Infez Med. 2012 Sep;20(3):211-3.
Histoplasma capsulatum is an opportunistic dimorphic fungus responsible for most often self-limiting or flu-like infections but potentially lethal in immunocompromised hosts. Histoplasmosis is rare in Europe. We reported a case of disseminated histoplasmosis in an African HIV patient with a leprosy-like primary cutaneous presentation and involvement of lungs, brain, limphnodes and eye. The therapy with liposomial B amphotericin and itraconazole led to a prompt resolution of the symptoms.
荚膜组织胞浆菌是一种机会性双相真菌,常引起自限性或流感样感染,但在免疫功能低下的宿主中可能致命。组织胞浆菌病在欧洲很少见。我们报告了一例非洲艾滋病患者发生播散性组织胞浆菌病,其最初表现为麻风样皮肤损害,并累及肺、脑、淋巴结和眼。脂质体两性霉素B和伊曲康唑治疗使症状迅速缓解。