Zhao Feng, Zeng Yongming, Peng Gang, Yu Renqiang, Peng Shengkun, Tan Huan, Liu Xiao, Wang Jie
Department of Radiology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
J Comput Assist Tomogr. 2012 Sep-Oct;36(5):523-7. doi: 10.1097/RCT.0b013e318266aa71.
The purpose of this study was to compare chest digital tomosynthesis (DTS) and multidetector computed tomography (MDCT) for the detection of pulmonary ground-glass opacity (GGO) nodules and estimation of radiation dose using an anthropomorphic chest phantom and simulated nodules.
A male anthropomorphic chest phantom equipped with thermoluminescent dosimeters and simulated pulmonary nodules showing GGO was scanned by MDCT and DTS. The organic radiation doses were recorded and converted into effective doses. The density, diameter, and position of pulmonary nodules were reviewed; and the sensitivities of nodule detection were compared using the Fisher exact test. The radiation dose levels of DTS and MDCT were compared using paired t tests.
The sensitivities of nodule detection by DTS and MDCT were 60% and 80%, respectively (P < 0.05), whereas the sensitivities of detection of -630-Hounsfield unit (HU) GGO nodules were 73.3% and 86.7%, respectively (P > 0.05), and the detection sensitivities of 5- and 8-mm diameter -800 HU GGO nodules were 33.3% and 58.3%, respectively (P < 0.05). The effective doses of DTS and MDCT were 0.65 and 7.71 mSv, respectively, and the mean effective dose of DTS for the chest was 91.6% lower than that of MDCT.
Multidetector computed tomography is preferable to DTS for the detection of GGO pulmonary nodules. Although the detection sensitivities of DTS and MDCT were similar for the nodules with a density of -630 HU, the detection sensitivity of MDCT was significantly superior to that of DTS for the 5- and 8-mm nodules with a density of -800 HU. The mean effective dose of DTS to the chest was significantly lower than that of MDCT.
本研究旨在使用人体胸部模型和模拟结节，比较胸部数字断层合成（DTS）和多排螺旋计算机断层扫描（MDCT）检测肺磨玻璃密度影（GGO）结节的能力以及估算辐射剂量。
使用配备热释光剂量计的男性人体胸部模型和显示GGO的模拟肺结节，进行MDCT和DTS扫描。记录器官辐射剂量并转换为有效剂量。观察肺结节的密度、直径和位置；采用Fisher精确检验比较结节检测的敏感性。采用配对t检验比较DTS和MDCT的辐射剂量水平。
DTS和MDCT检测结节的敏感性分别为60%和80%（P<0.05），而检测-630亨氏单位（HU）GGO结节的敏感性分别为73.3%和86.7%（P>0.05），直径5 mm和8 mm、密度-800 HU的GGO结节的检测敏感性分别为33.3%和58.3%（P<0.05）。DTS和MDCT的有效剂量分别为0.65和7.71 mSv，胸部DTS的平均有效剂量比MDCT低91.6%。
对于检测GGO肺结节，多排螺旋计算机断层扫描优于DTS。虽然密度为-630 HU的结节，DTS和MDCT的检测敏感性相似，但对于密度为-800 HU、直径5 mm和8 mm的结节，MDCT的检测敏感性显著优于DTS。胸部DTS的平均有效剂量显著低于MDCT。
