• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

下一代数字胸部断层合成成像。

Next-generation digital chest tomosynthesis.

作者信息

Gange Christopher, Ku Jamie, Gosangi Babina, Liu Jianqiang, Maolinbay Manat

机构信息

Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut, United States.

Product Development, Aixscan Inc., Sunnyvale, California, United States.

出版信息

J Clin Imaging Sci. 2024 Jun 26;14:22. doi: 10.25259/JCIS_4_2024. eCollection 2024.

DOI:10.25259/JCIS_4_2024
PMID:38975057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11225395/
Abstract

The objective of this study was to demonstrate the performance characteristics and potential utility of a novel tomosynthesis device as applied to imaging the chest, specifically relating to lung nodules. The imaging characteristics and quality of a novel digital tomosynthesis prototype system was assessed by scanning, a healthy volunteer, and an andromorphic lung phantom with different configurations of simulated pulmonary nodules. The adequacy of nodule detection on the phantoms was rated by chest radiologists using a standardized scale. Results from using this tomosynthesis device demonstrate in plane resolution of 16lp/cm, with estimated effective radiation doses of 90% less than low dose CT. Nodule detection was adequate across various anatomic locations on a phantom. These proof-of-concept tests showed this novel tomosynthesis device can detect lung nodules with low radiation dose to the patient. This technique has potential as an alternative to low dose chest CT for lung nodule screening and tracking.

摘要

本研究的目的是证明一种新型断层合成设备应用于胸部成像，特别是与肺结节相关成像时的性能特征和潜在效用。通过对一名健康志愿者和一个带有不同配置模拟肺结节的仿真肺模型进行扫描，评估了一种新型数字断层合成原型系统的成像特征和质量。胸部放射科医生使用标准化量表对模型上结节检测的充分性进行评分。使用该断层合成设备的结果表明，其平面分辨率为16lp/cm，估计有效辐射剂量比低剂量CT少90%。在模型的各个解剖位置，结节检测都是充分的。这些概念验证测试表明，这种新型断层合成设备能够以低辐射剂量检测患者的肺结节。这项技术有潜力作为低剂量胸部CT的替代方法用于肺结节筛查和跟踪。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/65c9835528cb/JCIS-14-22-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/d3abb95d2305/JCIS-14-22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/514fb355fca9/JCIS-14-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/463e6e27e253/JCIS-14-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/ae6aedbcb9ba/JCIS-14-22-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/8afc53b55544/JCIS-14-22-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/6d2a1cd949d4/JCIS-14-22-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/b2b5dde73e22/JCIS-14-22-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/4ae5d05a9421/JCIS-14-22-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/06c089e33a01/JCIS-14-22-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/c091f9a03aea/JCIS-14-22-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/b0e93d8302c3/JCIS-14-22-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/03ed225b919a/JCIS-14-22-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/d452dc31a991/JCIS-14-22-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/0fa38103ca75/JCIS-14-22-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/65c9835528cb/JCIS-14-22-g015.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/d3abb95d2305/JCIS-14-22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/514fb355fca9/JCIS-14-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/463e6e27e253/JCIS-14-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/ae6aedbcb9ba/JCIS-14-22-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/8afc53b55544/JCIS-14-22-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/6d2a1cd949d4/JCIS-14-22-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/b2b5dde73e22/JCIS-14-22-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/4ae5d05a9421/JCIS-14-22-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/06c089e33a01/JCIS-14-22-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/c091f9a03aea/JCIS-14-22-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/b0e93d8302c3/JCIS-14-22-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/03ed225b919a/JCIS-14-22-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/d452dc31a991/JCIS-14-22-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/0fa38103ca75/JCIS-14-22-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7223/11225395/65c9835528cb/JCIS-14-22-g015.jpg

相似文献

1
Next-generation digital chest tomosynthesis.下一代数字胸部断层合成成像。
J Clin Imaging Sci. 2024 Jun 26;14:22. doi: 10.25259/JCIS_4_2024. eCollection 2024.
2
Detection of Pulmonary Nodule Growth with Chest Tomosynthesis: A Human Observer Study Using Simulated Nodules.胸部断层合成检测肺结节生长：使用模拟结节的人体观察者研究。
Acad Radiol. 2019 Apr;26(4):508-518. doi: 10.1016/j.acra.2018.05.004. Epub 2018 Jun 19.
3
Multi-Institutional Evaluation of Digital Tomosynthesis, Dual-Energy Radiography, and Conventional Chest Radiography for the Detection and Management of Pulmonary Nodules.数字断层合成、双能X线摄影及传统胸部X线摄影对肺结节检测与管理的多机构评估
Radiology. 2017 Jan;282(1):236-250. doi: 10.1148/radiol.2016150497. Epub 2016 Jul 19.
4
Development of a chest digital tomosynthesis R/F system and implementation of low-dose GPU-accelerated compressed sensing (CS) image reconstruction.胸部数字断层合成 R/F 系统的开发及低剂量 GPU 加速压缩感知（CS）图像重建的实现。
Med Phys. 2018 May;45(5):1871-1888. doi: 10.1002/mp.12843. Epub 2018 Mar 23.
5
Digital tomosynthesis of the chest for lung nodule detection: interim sensitivity results from an ongoing NIH-sponsored trial.用于肺结节检测的胸部数字断层合成成像：一项正在进行的由美国国立卫生研究院资助的试验的中期敏感性结果
Med Phys. 2008 Jun;35(6):2554-7. doi: 10.1118/1.2937277.
6
Sensitivity of Thoracic Digital Tomosynthesis (DTS) for the Identification of Lung Nodules.胸部数字断层合成（DTS）对肺结节的识别敏感度。
J Digit Imaging. 2016 Feb;29(1):141-7. doi: 10.1007/s10278-015-9818-0.
7
Comparison of chest radiography, chest digital tomosynthesis and low dose MDCT to detect small ground-glass opacity nodules: an anthropomorphic chest phantom study.胸部 X 线摄影、胸部数字断层合成与低剂量 MDCT 检测磨玻璃密度小结节的比较：人体胸部体模研究。
Eur Radiol. 2014 Dec;24(12):3269-76. doi: 10.1007/s00330-014-3376-6. Epub 2014 Aug 6.
8
Experimental study of detection of nodules showing ground-glass opacity and radiation dose by using anthropomorphic chest phantom: digital tomosynthesis and multidetector CT.使用人体胸部模型对磨玻璃结节检测及辐射剂量的实验研究：数字断层合成与多排螺旋CT
J Comput Assist Tomogr. 2012 Sep-Oct;36(5):523-7. doi: 10.1097/RCT.0b013e318266aa71.
9
Feasibility of a prototype carbon nanotube enabled stationary digital chest tomosynthesis system for identification of pulmonary nodules by pulmonologists.一种启用原型碳纳米管的固定式数字胸部断层合成系统供肺科医生识别肺结节的可行性。
J Thorac Dis. 2022 Feb;14(2):257-268. doi: 10.21037/jtd-21-1381.
10
EFFECT OF RADIATION DOSE LEVEL ON ACCURACY AND PRECISION OF MANUAL SIZE MEASUREMENTS IN CHEST TOMOSYNTHESIS EVALUATED USING SIMULATED PULMONARY NODULES.使用模拟肺结节评估辐射剂量水平对胸部断层合成中手动尺寸测量准确性和精密度的影响。
Radiat Prot Dosimetry. 2016 Jun;169(1-4):188-98. doi: 10.1093/rpd/ncw041. Epub 2016 Mar 17.

引用本文的文献

1
Beyond the numbers: How Journal of Clinical Imaging Science is shaping the future of radiology publishing.数字之外：《临床影像科学杂志》如何塑造放射学出版的未来。
J Clin Imaging Sci. 2025 Jul 28;15:27. doi: 10.25259/JCIS_148_2025. eCollection 2025.

本文引用的文献

1
QUANTIFICATION OF PULMONARY PATHOLOGY IN CYSTIC FIBROSIS-COMPARISON BETWEEN DIGITAL CHEST TOMOSYNTHESIS AND COMPUTED TOMOGRAPHY.囊性纤维化肺部病变的定量分析——数字胸部断层合成与计算机断层扫描的比较。
Radiat Prot Dosimetry. 2021 Oct 12;195(3-4):434-442. doi: 10.1093/rpd/ncab017.
2
Digital tomosynthesis and ground glass nodules: Optimization of acquisition protocol. A phantom study.数字断层合成与磨玻璃结节：采集方案的优化。一项体模研究。
Radiography (Lond). 2021 May;27(2):574-580. doi: 10.1016/j.radi.2020.11.019. Epub 2020 Dec 16.
3
Determination of radiation dose and low-dose protocol for digital chest tomosynthesis using radiophotoluminescent (RPL) glass dosimeters.
使用放射性光致发光（RPL）玻璃剂量计测定数字胸部断层合成的放射剂量和低剂量方案。
Phys Med. 2020 May;73:13-21. doi: 10.1016/j.ejmp.2020.03.024. Epub 2020 Apr 9.
4
Development and validation of image quality scoring criteria (IQSC) for pediatric CT: a preliminary study.儿科CT图像质量评分标准（IQSC）的制定与验证：一项初步研究。
Insights Imaging. 2019 Sep 23;10(1):95. doi: 10.1186/s13244-019-0769-8.
5
The Landscape of US Lung Cancer Screening Services.美国肺癌筛查服务全景
Chest. 2019 May;155(5):900-907. doi: 10.1016/j.chest.2018.10.039. Epub 2018 Nov 9.
6
Limitations of Detecting Small Solid Lung Nodules by Using Digital Chest Tomosynthesis.使用数字化胸部断层合成技术检测肺部小实性结节的局限性
Radiology. 2018 Jun;287(3):1028-1029. doi: 10.1148/radiol.2018180144. Epub 2018 Apr 3.
7
Changing Utilization of Noninvasive Diagnostic Imaging Over 2 Decades: An Examination Family-Focused Analysis of Medicare Claims Using the Neiman Imaging Types of Service Categorization System.二十年来无创性诊断影像学利用的变化：使用 Neiman 影像学服务类型分类系统对医疗保险索赔进行以家庭为中心的分析
AJR Am J Roentgenol. 2018 Feb;210(2):364-368. doi: 10.2214/AJr17.18214. Epub 2017 Dec 8.
8
The advantage of digital tomosynthesis for pulmonary nodule detection concerning influence of nodule location and size: a phantom study.数字断层合成技术在肺结节检测中关于结节位置和大小影响的优势：一项体模研究
Clin Radiol. 2017 Sep;72(9):796.e1-796.e8. doi: 10.1016/j.crad.2017.03.022. Epub 2017 Apr 25.
9
Comparison of digital tomosynthesis and chest radiography for the detection of pulmonary nodules: systematic review and meta-analysis.数字断层合成与胸部X线摄影在检测肺结节方面的比较：系统评价与Meta分析
Br J Radiol. 2016 Dec;89(1068):20160421. doi: 10.1259/bjr.20160421. Epub 2016 Oct 19.
10
Multi-Institutional Evaluation of Digital Tomosynthesis, Dual-Energy Radiography, and Conventional Chest Radiography for the Detection and Management of Pulmonary Nodules.数字断层合成、双能X线摄影及传统胸部X线摄影对肺结节检测与管理的多机构评估
Radiology. 2017 Jan;282(1):236-250. doi: 10.1148/radiol.2016150497. Epub 2016 Jul 19.