Department of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, 3010 Bern, Switzerland.
J Bone Joint Surg Am. 2012 Sep 5;94(17):1559-67. doi: 10.2106/JBJS.K.00444.
The aims of the study were (1) to determine the cumulative two to twenty-year survivorship of the hip after open reduction and internal fixation of displaced acetabular fractures, (2) to identify factors predicting conversion to total hip arthroplasty or hip arthrodesis, and (3) to create a predictive model that calculates an individual's probability of early need for total hip arthroplasty or hip arthrodesis.
Eight hundred and sixteen acetabular fractures treated with open reduction and internal fixation by one surgeon over a twenty-six-year period were analyzed. Cumulative two to twenty-year Kaplan-Meier survivorship analyses of the hip, including best and worst-case scenarios, were performed with total hip arthroplasty or hip arthrodesis as the end point. Univariate and multivariate Cox regression analyses were performed to identify negative predictors, which were then used to construct a nomogram for predicting an individual's probability of needing an early total hip arthroplasty.
The cumulative twenty-year survivorship of the 816 hips available for follow-up was 79% at twenty years. The best and worst-case scenarios corresponded to cumulative twenty-year survivorship of 86% and 52%, respectively. Significant independent negative predictors were nonanatomical fracture reduction, an age of more than forty years, anterior hip dislocation, postoperative incongruence of the acetabular roof, involvement of the posterior acetabular wall, acetabular impaction, a femoral head cartilage lesion, initial displacement of the articular surface of ≥ 20 mm, and utilization of the extended iliofemoral approach.
Open reduction and internal fixation of displaced acetabular fractures was able to successfully prevent the need for subsequent total hip arthroplasty within twenty years in 79% of the patients. The results represent benchmark comparative data for any future and past studies on the outcome of surgical fixation of acetabular fractures.
本研究的目的是:(1)确定切开复位内固定治疗移位髋臼骨折后髋关节的 2 至 20 年累积生存率;(2)确定预测转换为全髋关节置换术或髋关节融合术的因素;(3)建立一个预测模型,计算个体早期需要全髋关节置换术或髋关节融合术的概率。
对一位医生在 26 年期间采用切开复位内固定治疗的 816 例髋臼骨折进行了分析。采用Kaplan-Meier 生存分析方法对髋关节进行了 2 至 20 年的累积生存率分析,包括最佳和最差情况,并以全髋关节置换术或髋关节融合术为终点。进行单变量和多变量Cox 回归分析以确定负性预测因子,然后使用该因子构建预测个体早期需要全髋关节置换术概率的列线图。
816 例可随访髋关节的 20 年累积生存率为 79%。最佳和最差情况对应的 20 年累积生存率分别为 86%和 52%。显著的独立负性预测因子是非解剖复位、年龄大于 40 岁、髋关节前脱位、术后髋臼顶不匹配、髋臼后侧壁受累、髋臼撞击、股骨头软骨损伤、关节面初始移位≥20mm 以及采用扩展的髂股入路。
切开复位内固定治疗移位髋臼骨折,在 79%的患者中可成功避免 20 年内需要后续全髋关节置换术。该结果为任何未来和过去关于髋臼骨折手术固定结果的研究提供了基准比较数据。