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目前治疗儿童重症接触性皮炎的策略。

Current strategies in treating severe contact dermatitis in pediatric patients.

机构信息

Section of Allergy and Immunology, Winthrop University Hospital, Mineola, NY 11501, USA.

出版信息

Curr Allergy Asthma Rep. 2012 Dec;12(6):599-606. doi: 10.1007/s11882-012-0305-0.

Abstract

Allergic contact dermatitis in children is underdiagnosed and undertreated, and its incidence is increasing. Appropriate history taking and the suspicion for allergic contact dermatitis is essential, and patch testing remains the gold standard in diagnosis. Avoidance of the offending allergen, once identified, is the first goal of treatment. Medical therapies include topical corticosteroid and topical immunomodulators. In severe cases, oral corticosteroids or immunomodulators are utilized, although prospective randomized trials for the treatment of this disease in children are lacking. A PubMed literature search was performed to identify publications on allergic contact dermatitis in the pediatric population with the keywords: dermatitis, children, allergic contact dermatitis, pediatrics, contact hypersensitivity, contact allergy, treatment, and management. This review will address the major principles behind the diagnosis and management of this disease in the pediatric population, and highlight useful strategies that may result in improved treatment of this condition.

摘要

儿童过敏性接触性皮炎诊断不足且治疗不足,其发病率正在上升。适当的病史采集和对过敏性接触性皮炎的怀疑至关重要,斑贴试验仍然是诊断的金标准。一旦确定过敏原,避免接触是治疗的首要目标。医疗治疗包括局部皮质类固醇和局部免疫调节剂。在严重的情况下,会使用口服皮质类固醇或免疫调节剂,尽管缺乏针对儿童这种疾病的前瞻性随机试验。进行了一项 PubMed 文献检索,以使用关键词:皮炎、儿童、过敏性接触性皮炎、儿科学、接触性超敏反应、接触过敏、治疗和管理,来识别有关儿科人群中过敏性接触性皮炎的出版物。这篇综述将讨论在儿科人群中诊断和管理这种疾病的主要原则,并强调可能改善这种疾病治疗的有用策略。

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