Khakshoor Hamid, Moghaddam Ali Akbar Saber, Vejdani Amir Hossein, Armstrong Blair K, Moshirfar Majid
Eye Research Center, Khatam Al-Anbia Hospital, Department of Ophthalmology, Mashhad University of Medical Sciences, Mashhad, Iran.
Oman J Ophthalmol. 2012 May;5(2):109-11. doi: 10.4103/0974-620X.99375.
Foodborne botulism is a serious condition caused by Clostridium botulinum neurotoxin. Clinically, botulism presents as bilateral cranial nerve neuropathy and descending paralysis. We report a unique presentation of botulism to remind clinicians of this potentially fatal condition. In this observational case report initial evaluation showed only esodeviation. This progressed to unilateral cranial nerve six (CN VI) paresis along with systemic signs. Clinical diagnosis was made based on in-depth history and concurrent symptoms in three other patients. Foodborne botulism presenting as diplopia and unilateral motility deficits is rare and can represent a diagnostic and therapeutic challenge to the ophthalmologist.
食源性肉毒中毒是由肉毒梭菌神经毒素引起的一种严重疾病。临床上,肉毒中毒表现为双侧颅神经神经病变和下行性麻痹。我们报告了一例独特的肉毒中毒病例,以提醒临床医生注意这种潜在的致命疾病。在这份观察性病例报告中,初步评估仅显示内斜视。随后发展为单侧第六颅神经(CN VI)麻痹并伴有全身症状。临床诊断基于对另外三名患者的深入病史和并发症状做出。以复视和单侧运动功能障碍为表现的食源性肉毒中毒较为罕见,可能给眼科医生带来诊断和治疗挑战。