Hamzah Azhar Amir, Rahman Mohd Nor Gohar, Daud Mohamed Ashraf Mohamed, Mahamood Zainal
Unit Urology, Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
Malays J Med Sci. 2007 Jul;14(2):67-71.
Patients with Benign Prostatic Hyperplasia (BPH) commonly presents with lower urinary tract symptoms (LUTS), which can be of obstructive symptoms such as hesitancy, incomplete voiding, post void dribbling or of irritative symptoms such as urgency, frequency and nocturia. Various recent studies indicate that nocturia is a very important and bothersome lower urinary tract symptom especially among patients with Benign Prostatic Hyperplasia (BPH). The aims of the study was to determine the frequency of common urinary symptoms among patients with BPH in HUSM as well as to evaluate the extent of bothersomeness of each and every symptom to these patients. This study too was aimed at evaluating the success of TURP in resolving pre operative LUTS. This was a questionnaire-based survey using a validated ICSBPH model whereby patients with BPH were selected and quizzed personally by an investigator. A subset of patients who had undergone TURP were further questioned regarding their satisfaction with the procedure. When nocturia is defined as waking up at night once or more to pass urine, the prevalence of nocturia was about 90%, but only 1 in 6 patients considered this is a very serious symptom. Even if the definition was changed to waking up twice or more, the prevalence is still quite high at over 80%. Urgency were noted in half of the patients, but only a quarter of them consider it a serious problem. 1 in 5 patients experienced significant leak and almost all consider it serious. About one third of the studied population had to be catheterized due to urinary obstruction and interestingly only about half of them considered it as a very serious event. Overall, a great majority of these patients considered suffering from these urinary symptoms for the rest of their life as very devastating. This study conclude that although the prevalence of nocturia was high among BPH patients, but it was not considered serious by majority of them. In fact, LUTS in our BPH patients did not differ much from BPH patients elsewhere. On the whole, TURP resolved most of the LUTS effectively.
良性前列腺增生（BPH）患者通常会出现下尿路症状（LUTS），这些症状可能是梗阻性症状，如排尿犹豫、排尿不尽、尿后滴沥，也可能是刺激性症状，如尿急、尿频和夜尿症。最近的各种研究表明，夜尿症是一种非常重要且令人困扰的下尿路症状，尤其是在良性前列腺增生（BPH）患者中。该研究的目的是确定胡先汉姆大学医学中心（HUSM）BPH患者常见泌尿系统症状的发生率，并评估每种症状对这些患者的困扰程度。这项研究还旨在评估经尿道前列腺切除术（TURP）在解决术前LUTS方面的成功率。这是一项基于问卷调查的研究，使用经过验证的国际前列腺症状评分（ICSBPH）模型，选择BPH患者并由一名研究人员亲自进行询问。对一部分接受过TURP的患者进一步询问他们对该手术的满意度。当将夜尿症定义为夜间醒来排尿一次或更多次时，夜尿症的患病率约为90%，但只有六分之一的患者认为这是一个非常严重的症状。即使将定义改为夜间醒来两次或更多次，患病率仍然相当高，超过80%。一半的患者有尿急症状，但只有四分之一的患者认为这是一个严重问题。五分之一的患者有明显漏尿，几乎所有人都认为这很严重。约三分之一的研究人群因尿路梗阻需要导尿，有趣的是，只有约一半的人认为这是一件非常严重的事情。总体而言，这些患者中的绝大多数认为余生遭受这些泌尿系统症状是非常具有毁灭性的。这项研究得出结论，虽然BPH患者中夜尿症的患病率很高，但大多数患者并不认为它很严重。事实上，我们的BPH患者的LUTS与其他地方的BPH患者没有太大差异。总体而言，TURP有效地解决了大多数LUTS。
