Eckhardt M D, van Venrooij G E, van Melick H H, Boon T A
Department of Urology, University Medical Center Utrecht, The Netherlands.
J Urol. 2001 Aug;166(2):563-8.
We established the prevalence and bothersomeness of symptoms and their impact on well-being in a large group of strictly selected men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH).
Included in our study were 475 consecutive men who met the criteria of the International Consensus Committee on BPH and voided more than 150 ml. during uroflowmetry. International Prostate Symptom Scores and quality of life score were determined. We included the 7 bothersomeness questions of the Symptom Problem Index and the 4 of the BPH Impact Index of the American Urological Association Measurement Committee. These questions refer to the degree of bothersomeness caused by urinary problems and how they affect various health domains.
The symptoms with the highest prevalence based on mean scores were weak urinary stream, frequency and urgency. Urgency, nocturia and hesitancy were the most bothersome symptoms. Patients were only discouraged from performing normal daily activity when the symptom index exceeded 20. Incomplete emptying and frequency bothersomeness correlated strongly, and weak urinary stream and hesitancy bothersomeness correlated weakly with all health and quality of life domains.
Weak urinary stream, frequency and urgency were the most prevalent symptoms, while urgency, nocturia and hesitancy were the most bothersome symptoms. In contrast to weak urinary stream and hesitancy, the bothersomeness of incomplete emptying and frequency was strongly associated with well-being.
我们在一大群经严格筛选、有提示良性前列腺增生（BPH）的下尿路症状的男性中，确定了症状的患病率、困扰程度及其对幸福感的影响。
我们的研究纳入了475名连续的男性，他们符合BPH国际共识委员会的标准，并且在尿流率测定期间排尿量超过150毫升。测定了国际前列腺症状评分和生活质量评分。我们纳入了症状问题指数的7个困扰问题以及美国泌尿外科学会测量委员会的BPH影响指数的4个问题。这些问题涉及尿路问题引起的困扰程度以及它们如何影响各个健康领域。
基于平均得分，患病率最高的症状是尿流无力、尿频和尿急。尿急、夜尿和排尿犹豫是最困扰人的症状。只有当症状指数超过20时，患者才会因症状而不愿进行正常的日常活动。排尿不完全和尿频困扰与所有健康和生活质量领域的相关性很强，而尿流无力和排尿犹豫困扰与这些领域的相关性较弱。
尿流无力、尿频和尿急是最常见的症状，而尿急、夜尿和排尿犹豫是最困扰人的症状。与尿流无力和排尿犹豫不同，排尿不完全和尿频的困扰与幸福感密切相关。
