一名患有格雷夫斯病的女性的早发性乳腺癌。
Early-onset breast cancer in a woman with Graves' disease.
作者信息
Siegler James E, Li Xinying, Jones Steven D, Kandil Emad
机构信息
Tulane University School of Medicine Changsha, China.
出版信息
Int J Clin Exp Med. 2012;5(4):358-62. Epub 2012 Aug 22.
Abstract
The relationship between thyroid and breast diseases has been documented, but the clinical significance of Graves' disease and breast cancer is unclear. We present a young patient with a history of Graves' disease who developed a multicentric infiltrating ductal carcinoma of the breast several months after discontinuing her treatment with propylthiouracil. Early-onset breast cancer in women without a family history of early breast cancer may be related to hyperthyroidism. The relationship between thyroid hormone and estrogen is discussed.
摘要
甲状腺与乳腺疾病之间的关系已有文献记载，但格雷夫斯病与乳腺癌的临床意义尚不清楚。我们报告一名有格雷夫斯病病史的年轻患者，在停用丙硫氧嘧啶治疗数月后发生了多中心浸润性乳腺导管癌。无早期乳腺癌家族史的女性早发性乳腺癌可能与甲状腺功能亢进有关。本文还讨论了甲状腺激素与雌激素之间的关系。
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本文引用的文献
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Thyroid hormone and breast carcinoma. Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma.甲状腺激素与乳腺癌。原发性甲状腺功能减退与原发性乳腺癌发病率降低有关。
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