Saengsawang Phubet, Promthet Supannee, Bradshaw Peter
Department of Epidemiology, Faculty of Public Health, Khon Kaen University, Thailand.
Asian Pac J Cancer Prev. 2012;13(7):3399-402. doi: 10.7314/apjcp.2012.13.7.3399.
A liver fluke, Opisthorchis viverrrini (OV), is the major cause of the high incidence of cholangiocarcinoma in Thailand. The prevalence of OV infection remains high in various parts of the country, especially in Northeast Thailand and particularly in wetland rural areas where a large proportion of the community work in agriculture and continue the traditional practice of eating raw or undercooked cyprinoid fish products. The national control program seems to have had little impact in many of these areas, and it has been difficult to make precise assessments of the overall effectiveness of the program. This paper is the first report of prospective research project designed to monitor the impact of the national control program in rural communities located in a northeastern province and at high risk of OV infection. The participants in this initial survey were 1,569 villagers, aged 20-65 years, living in two subdistricts of Yasothon Province. Stool examinations showed that 38.68% were infected with OV. Males were slightly more likely to be infected than females, but the difference was not statistically significant. Infection was found to be positively associated with age in both males and females. The preliminary data indicate that the population selected for study is suitable for the purpose of the monitoring project.
肝吸虫，即泰国肝吸虫（OV），是泰国胆管癌高发的主要原因。在该国各地，尤其是泰国东北部，特别是在湿地农村地区，OV感染率仍然很高，在这些地区，很大一部分社区从事农业工作，并延续食用生的或未煮熟的鲤科鱼类产品的传统习惯。国家控制计划在许多这些地区似乎收效甚微，而且很难对该计划的整体效果进行精确评估。本文是关于一项前瞻性研究项目的首次报告，该项目旨在监测国家控制计划对位于东北部一个省份且OV感染风险高的农村社区的影响。本次初步调查的参与者为1569名年龄在20至65岁之间、居住在也梭通府两个区的村民。粪便检查显示，38.68%的人感染了OV。男性感染的可能性略高于女性，但差异无统计学意义。在男性和女性中，感染均与年龄呈正相关。初步数据表明，所选研究人群适合该监测项目的目的。
