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吸烟量和尼古丁依赖对青少年吸烟规律的时变影响。

Time-varying effects of smoking quantity and nicotine dependence on adolescent smoking regularity.

机构信息

Psychology Department, Wesleyan University, Middletown, CT 06459, USA.

出版信息

Drug Alcohol Depend. 2013 Mar 1;128(3):230-7. doi: 10.1016/j.drugalcdep.2012.08.026. Epub 2012 Sep 17.

DOI:10.1016/j.drugalcdep.2012.08.026
PMID:22995764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3538104/
Abstract

BACKGROUND

Little is known about time-varying effects of smoking quantity and nicotine dependence on the regularity of adolescent smoking behavior.

METHODS

The sample was drawn from the Social and Emotional Contexts of Adolescent Smoking Patterns Study which followed adolescent smokers over 5 assessment waves spanning 48 months. Participants included former experimenters (smoked <100 cigarettes/lifetime but did not smoke in past 90 days), recent experimenters (smoked <100 cigarettes/lifetime and smoked in past 90 days), and current smokers (smoked >100 cigarettes/lifetime and smoked in past 30 days). Mixed-effects regression models were run to examine the time-varying effects of smoking quantity and nicotine dependence on regularity of smoking behavior, as measured by number of days smoked.

RESULTS

Smoking quantity and nicotine dependence were each found to be significantly associated with regularity of adolescent smoking and the size of each effect exhibited significant variation over time. The effect of smoking quantity decreased across time for each smoking group, while the effect of nicotine dependence increased across time for former and recent experimenters. By the 48-month follow-up, the effects of smoking quantity and nicotine dependence had each stabilized across groups.

CONCLUSIONS

This study reveals that smoking quantity and nicotine dependence are not static risk factors for the development of more regular smoking patterns. At low levels of smoking when nicotine dependence symptoms are less common, smoking quantity is a stronger predictor of increased regularity of smoking, while for more experienced smokers, nicotine dependence predicts further increases in regularity.

摘要

背景

关于吸烟量和尼古丁依赖随时间变化对青少年吸烟行为规律的影响,目前知之甚少。

方法

该样本来自青少年吸烟模式的社会和情感背景研究,该研究在 48 个月的时间内对青少年吸烟者进行了 5 次评估。参与者包括前实验者(吸烟<100 支/终生但在过去 90 天内未吸烟)、近期实验者(吸烟<100 支/终生且在过去 90 天内吸烟)和当前吸烟者(吸烟>100 支/终生且在过去 30 天内吸烟)。采用混合效应回归模型来检验吸烟量和尼古丁依赖对吸烟行为规律(以吸烟天数衡量)的时变影响。

结果

吸烟量和尼古丁依赖均与青少年吸烟行为的规律性显著相关,且每种效应的大小随时间显著变化。对于每个吸烟群体,吸烟量的效应随时间降低,而尼古丁依赖的效应随时间增加,对于前实验者和近期实验者。在 48 个月的随访中,吸烟量和尼古丁依赖的效应在各组中均已稳定。

结论

本研究揭示了吸烟量和尼古丁依赖并不是形成更规律吸烟模式的静态危险因素。在尼古丁依赖症状不太常见的低吸烟水平时,吸烟量是增加吸烟规律性的更强预测因素,而对于更有经验的吸烟者,尼古丁依赖则预示着规律性的进一步增加。

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