Department of neurology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Stroke. 2012 Dec;43(12):3375-7. doi: 10.1161/STROKEAHA.112.671453. Epub 2012 Sep 20.
The purpose of this study was to determine the incidence of adult cerebral venous thrombosis.
A retrospective cross-sectional study was conducted among all 19 hospitals located in 2 Dutch provinces serving 3.1 million people. Adult cerebral venous thrombosis cases diagnosed between January 1, 2008, and December 31, 2010, were identified using the Dutch financial coding system for hospital care and the International Classification of Diseases, 9th Revision. Medical records of potential patients were hand searched to identify cerebral venous thrombosis cases. The Dutch National Bureau for Statistics provided population figures of the 2 provinces during 2008 to 2010.
Among 9270 potential cases, we identified 147 patients diagnosed with cerebral venous thrombosis. Of these, 53 patients did not meet the inclusion criteria; therefore, 94 patients were included in the analysis. The overall incidence was 1.32 per 100 000 person-years (95% CI, 1.06-1.61). Among women between the ages of 31 and 50 years, the incidence was 2.78 (95% CI, 1.98-3.82).
The incidence of cerebral venous thrombosis among adults is probably higher than previously believed.
本研究旨在确定成人脑静脉血栓形成的发病率。
对荷兰两个省的 19 家医院（共为 310 万人提供服务）进行回顾性的横断面研究。使用荷兰医院治疗财务编码系统和国际疾病分类第 9 版识别 2008 年 1 月 1 日至 2010 年 12 月 31 日诊断的成人脑静脉血栓病例。对潜在患者的病历进行手工搜索以确定脑静脉血栓病例。荷兰国家统计局提供了 2008 年至 2010 年这两个省的人口数据。
在 9270 例潜在病例中，我们确定了 147 例诊断为脑静脉血栓的患者。其中 53 例不符合纳入标准，因此纳入分析的患者有 94 例。总体发病率为每 100000 人年 1.32 例（95%可信区间，1.06-1.61）。在 31 岁至 50 岁的女性中，发病率为 2.78（95%可信区间，1.98-3.82）。
成人脑静脉血栓形成的发病率可能高于先前的估计。
