HUNT Research Center, Department of Public Health and General Practice, Faculty of Medicine, Norwegian, University of Science and Technology, Forskningsveien 2, 7600, Levanger, Norway.
BMC Public Health. 2012 Sep 22;12:820. doi: 10.1186/1471-2458-12-820.
Environment, health behavior, and genetic background are important in the development of obesity. Adolescents spend substantial part of daily leisure time on cultural and social activities, but knowledge about the effects of participation in such activities on weight is limited.
A number of 1450 adolescents from the Norwegian HUNT study (1995-97) were followed-up in 2006-08 as young adults. Phenotypic data on lifestyle and anthropometric measures were assessed using questionnaires and standardized clinical examinations. Genotypic information on 12 established obesity-susceptibility loci were available for analyses. Generalized estimating equations were used to examine the associations between cultural and social activities in adolescence and adiposity measures in young adulthood. In addition, interaction effects of a genetic predisposition score by leisure time activities were tested.
In girls, participation in cultural activities was negatively associated with waist circumference (WC) (B = -0.04, 95%CI: -0.08 to -0.00) and with waist-hip ratio (WHR) (B = -0.058, 95%CI: -0.11 to -0.01). However, participation in social activities was positively associated with WC (B = 0.040, CI: 0.00 to 0.08) in girls and with BMI (B = 0.027, CI: 0.00 to 0.05) in boys. The effect of the obesity-susceptibility genetic variants on anthropometric measures was lower in adolescents with high participation in cultural activities compared to adolescents with low participation.
This study suggests that the effects of cultural activities on body fat are different from the effects of participation in social activities. The protective influence of cultural activities in female adolescents against overweight in adulthood and their moderating effect on obesity-susceptibility genes suggest that even cultural activities may be useful in public health strategies against obesity.
环境、健康行为和遗传背景在肥胖的发展中起着重要作用。青少年在日常生活中会花费大量的闲暇时间参与文化和社交活动，但对于参与此类活动对体重的影响知之甚少。
挪威亨于特研究（1995-97 年）中的 1450 名青少年在 2006-08 年作为年轻人进行了随访。使用问卷和标准化临床检查评估生活方式和人体测量指标的表型数据。可用于分析 12 个已确定的肥胖易感性基因座的基因型信息。使用广义估计方程来检查青少年时期的文化和社交活动与成年早期肥胖指标之间的关联。此外，还测试了遗传易感性评分与休闲时间活动之间的交互作用。
在女孩中，参与文化活动与腰围（WC）（B=-0.04，95%CI：-0.08 至-0.00）和腰臀比（WHR）（B=-0.058，95%CI：-0.11 至-0.01）呈负相关。然而，在女孩中，参与社交活动与 WC（B=0.040，CI：0.00 至 0.08）和男孩中与 BMI（B=0.027，CI：0.00 至 0.05）呈正相关。与低参与度的青少年相比，高参与度的青少年的文化活动对肥胖易感性基因变异的影响较小。
本研究表明，文化活动对体脂的影响与参与社交活动的影响不同。文化活动对女性青少年超重的保护作用及其对肥胖易感性基因的调节作用表明，即使是文化活动也可能对防治肥胖的公共卫生策略有用。
