Department of Fundamental Microbiology, University of Lausanne, 1015 Lausanne, Switzerland.
Curr Opin Biotechnol. 2013 Jun;24(3):534-41. doi: 10.1016/j.copbio.2012.09.002. Epub 2012 Sep 19.
A wide variety of whole cell bioreporter and biosensor assays for arsenic detection has been developed over the past decade. The assays permit flexible detection instrumentation while maintaining excellent method of detection limits in the environmentally relevant range of 10-50 μg arsenite per L and below. New emerging trends focus on genetic rewiring of reporter cells and/or integration into microdevices for more optimal detection. A number of case studies have shown realistic field applicability of bioreporter assays.
在过去的十年中，已经开发出了各种各样的用于砷检测的全细胞生物报告器和生物传感器检测方法。这些检测方法在保持环境相关范围内（每升亚砷酸盐 10-50μg 及以下）的优异检测限的同时，允许灵活的检测仪器。新出现的趋势集中在报告细胞的遗传重新布线和/或集成到微器件中，以实现更优化的检测。一些案例研究表明，生物报告器检测方法具有实际的现场应用可能性。
