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针刺治疗脑卒中后吞咽障碍疗效的 Meta 分析。

A meta-analysis of the efficacy of acupuncture in treating dysphagia in patients with a stroke.

机构信息

Department of Rehabilitation, The First Affiliated Hospital of GuangXi Medical University, NanNing, China.

出版信息

Acupunct Med. 2012 Dec;30(4):291-7. doi: 10.1136/acupmed-2012-010155. Epub 2012 Sep 22.

DOI:10.1136/acupmed-2012-010155
PMID:23000511
Abstract

BACKGROUND

Dysphagia, or deglutition difficulty, is a common manifestation in patients with a stroke and its management is an important aspect of rehabilitation. Acupuncture, a complementary and alternative therapy, is the subject of growing public interest for treatment of stroke.

OBJECTIVE

A meta-analysis was performed to study the effect of acupuncture for treatment of dysphagia in patients affected by a stroke.

METHODS

Randomised controlled trials (RCTs) comparing acupuncture treatment with non-acupuncture treatment of dysphagia in patients with a stroke were identified from the databases of PubMed, Embase, Cochrane Library and CBM disc (China Biological Medicine Database). Eligible investigations were included and data on the effectiveness of acupuncture were extracted and synthesised by meta-analysis using RevMan 5.1.4. Results were expressed as OR for dichotomous data; 95% CIs were also calculated.

RESULTS

Seventy-two RCTs (3208 patients in the treatment group and 2926 patients in the control group) were identified. Details of randomisation and blinding were not reported and information on withdrawals and dropouts was missing in most of included reports. Meta-analysis showed that the effectiveness of treatment in the group receiving acupuncture was higher than that in the non-acupuncture group (OR=5.17, 95% CI 4.18 to 6.38; p<0.00001). However, the study quality was generally low and of insufficient quality to make recommendations about using acupuncture in the rehabilitation of patients with dysphagia due to stroke.

CONCLUSIONS

Acupuncture might be beneficial in the rehabilitation of patients with dysphagia caused by stroke, and the evidence justifies future high-quality studies.

摘要

背景

吞咽困难,即吞咽困难,是脑卒中患者的常见表现,其管理是康复的重要方面。针灸作为一种补充和替代疗法,越来越受到公众对治疗中风的关注。

目的

进行荟萃分析研究针灸治疗中风后吞咽困难的效果。

方法

从 PubMed、Embase、Cochrane 图书馆和 CBM disc(中国生物医学数据库)数据库中确定了比较针灸治疗与非针灸治疗中风患者吞咽困难的随机对照试验(RCT)。纳入了合格的研究,并使用 RevMan 5.1.4 对针灸疗效的数据进行提取和综合分析。结果以二项数据的 OR 表示;也计算了 95%CI。

结果

共确定了 72 项 RCT(治疗组 3208 例,对照组 2926 例)。未报告随机化和盲法的详细信息,大多数纳入的报告中缺少关于退出和脱落的信息。荟萃分析显示,接受针灸治疗的组的治疗效果高于非针灸组(OR=5.17,95%CI 4.18 至 6.38;p<0.00001)。然而,研究质量普遍较低,质量不足以推荐使用针灸治疗中风后吞咽困难患者。

结论

针灸可能对中风引起的吞咽困难患者的康复有益,证据支持未来进行高质量的研究。

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