McGettigan Benjamin David, Hew Meilyn, Phillips Elizabeth, McLean-Tooke Andrew
Department of Immunology, Royal Perth Hospital, Perth, Western Australia, Australia.
BMJ Case Rep. 2012 Sep 21;2012:bcr2012006638. doi: 10.1136/bcr-2012-006638.
A 63-year-old man was admitted for investigation of blurred vision and multiple ring-enhancing lesions on cranial MRI. Histopathological examination of tissue obtained at brain biopsy showed multiple Toxoplasma gondii cysts. He was started on a combination of sulphadiazine and pyrimethamine for cerebral toxoplasmosis and was subsequently diagnosed with HIV-1 infection. He then developed acute renal failure and flank pain and was diagnosed with bilateral vesico-uretric calculi requiring bilateral stent insertion. The retrieved renal calculi were negative for the common stones that are routinely tested for in our laboratory and had the macroscopic characteristics of a sulphadiazine stone. His renal failure responded to cessation of the sulphadiazine.
一名63岁男性因视力模糊及头颅磁共振成像（MRI）显示多发环形强化病灶入院检查。脑活检组织的组织病理学检查显示多个弓形虫囊肿。他开始接受磺胺嘧啶和乙胺嘧啶联合治疗脑弓形虫病，随后被诊断为HIV-1感染。之后他出现急性肾衰竭和胁腹疼痛，被诊断为双侧膀胱输尿管结石，需要双侧置入支架。取出的肾结石在我们实验室常规检测的常见结石中呈阴性，具有磺胺嘧啶结石的宏观特征。停用磺胺嘧啶后，他的肾衰竭症状有所缓解。
