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自由间歇步行训练对 2 型糖尿病患者血糖控制、身体成分和身体适应性的影响:一项随机对照试验。

The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients: a randomized, controlled trial.

机构信息

Centre of Inflammation and Metabolism, Department of Infectious Diseases and CMRC, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

出版信息

Diabetes Care. 2013 Feb;36(2):228-36. doi: 10.2337/dc12-0658. Epub 2012 Sep 21.

Abstract

OBJECTIVE

To evaluate the feasibility of free-living walking training in type 2 diabetic patients and to investigate the effects of interval-walking training versus continuous-walking training upon physical fitness, body composition, and glycemic control.

RESEARCH DESIGN AND METHODS

Subjects with type 2 diabetes were randomized to a control (n = 8), continuous-walking (n = 12), or interval-walking group (n = 12). Training groups were prescribed five sessions per week (60 min/session) and were controlled with an accelerometer and a heart-rate monitor. Continuous walkers performed all training at moderate intensity, whereas interval walkers alternated 3-min repetitions at low and high intensity. Before and after the 4-month intervention, the following variables were measured: VO(2)max, body composition, and glycemic control (fasting glucose, HbA(1c), oral glucose tolerance test, and continuous glucose monitoring [CGM]).

RESULTS

Training adherence was high (89 ± 4%), and training energy expenditure and mean intensity were comparable. VO(2)max increased 16.1 ± 3.7% in the interval-walking group (P < 0.05), whereas no changes were observed in the continuous-walking or control group. Body mass and adiposity (fat mass and visceral fat) decreased in the interval-walking group only (P < 0.05). Glycemic control (elevated mean CGM glucose levels and increased fasting insulin) worsened in the control group (P < 0.05), whereas mean (P = 0.05) and maximum (P < 0.05) CGM glucose levels decreased in the interval-walking group. The continuous walkers showed no changes in glycemic control.

CONCLUSIONS

Free-living walking training is feasible in type 2 diabetic patients. Continuous walking offsets the deterioration in glycemia seen in the control group, and interval walking is superior to energy expenditure-matched continuous walking for improving physical fitness, body composition, and glycemic control.

摘要

目的

评估 2 型糖尿病患者自由步行训练的可行性,并研究间歇步行训练与连续步行训练对身体适应性、身体成分和血糖控制的影响。

研究设计和方法

将 2 型糖尿病患者随机分为对照组(n = 8)、连续步行组(n = 12)和间歇步行组(n = 12)。训练组每周进行 5 次训练(每次 60 分钟),并使用加速度计和心率监测器进行控制。连续步行者以中等强度进行所有训练,而间歇步行者以低强度和高强度交替进行 3 分钟重复训练。干预前和干预后 4 个月,测量以下变量:最大摄氧量(VO₂max)、身体成分和血糖控制(空腹血糖、HbA1c、口服葡萄糖耐量试验和连续血糖监测[CGM])。

结果

训练依从性高(89 ± 4%),训练能量消耗和平均强度相当。间歇步行组的 VO₂max 增加了 16.1 ± 3.7%(P < 0.05),而连续步行组和对照组无变化。只有间歇步行组的体重和肥胖程度(体脂肪和内脏脂肪)降低(P < 0.05)。对照组的血糖控制恶化(平均 CGM 血糖水平升高和空腹胰岛素增加)(P < 0.05),而间歇步行组的平均(P = 0.05)和最大(P < 0.05)CGM 血糖水平降低。连续步行者的血糖控制无变化。

结论

自由步行训练在 2 型糖尿病患者中是可行的。连续步行可以抵消对照组血糖恶化的影响,而间歇步行在提高身体适应性、身体成分和血糖控制方面优于能量消耗匹配的连续步行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26b0/3554285/b32cb88d8ee5/228fig1.jpg

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