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双侧硬膜下血肿致中央疝后左旋多巴反应性帕金森综合征

Levodopa-responsive parkinsonism following central herniation due to bilateral subdural hematomas.

作者信息

Trosch R M, Ransom B R

机构信息

Department of Neurology, Yale University School of Medicine, New Haven, CT 06510.

出版信息

Neurology. 1990 Feb;40(2):376-7. doi: 10.1212/wnl.40.2.376.

Abstract

A 66-year-old man suffered bilateral subdural hematomas progressing to central herniation, despite repeated surgical evacuations. This eventually resolved, leaving him with a severe parkinsonian syndrome that was responsive to levodopa. MRI and CT showed midbrain compression from central herniation, and a follow-up MRI revealed thinning of the pars compacta. The clinical and radiologic evidence suggested that midbrain compression from central herniation was the probable cause of parkinsonism in this patient.

摘要

一名66岁男性尽管多次接受手术清除血肿,但仍出现双侧硬膜下血肿并进展为中央疝。最终病情得到缓解,但留下了对左旋多巴有反应的严重帕金森综合征。MRI和CT显示中央疝导致中脑受压,后续MRI显示黑质致密部变薄。临床和影像学证据表明,中央疝导致的中脑受压可能是该患者帕金森症的病因。

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