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继发于右侧颞叶出血的多巴反应性帕金森综合征

Dopa-responsive parkinsonism secondary to right temporal lobe haemorrahage.

作者信息

Ling Monica J, Aggarwal Arun, Morris John G L

机构信息

Department of Rehabilitation, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

出版信息

Mov Disord. 2002 Mar;17(2):402-4. doi: 10.1002/mds.10081.

Abstract

A 46-year-old man developed a symmetrical parkinsonian syndrome 7 weeks after large right temporal intracerebral haemorrhage resulting from a ruptured arteriovenous malformation. His signs included bradykinesia, rigidity, start hesitation, and poor postural reflexes, without a resting tremor. He also had signs of a Parinaud's syndrome. Computed tomography and magnetic resonance imaging of the brain demonstrated changes in the right temporal lobe associated with the haemorrhage but no abnormality of the basal ganglia or midbrain. Levodopa therapy produced a dramatic improvement within a few days of commencement. We postulate that the parkinsonism resulted from midbrain compression secondary to transtentorial herniation. Although parkinsonism is a rare complication of lobar intracerebral haemorrhage, it is important to recognise as it may be potentially treatable.

摘要

一名46岁男性在因动静脉畸形破裂导致右侧颞叶大量脑出血7周后出现对称性帕金森综合征。他的症状包括运动迟缓、僵硬、起始犹豫和姿势反射差,无静止性震颤。他还有帕里诺德综合征的症状。脑部计算机断层扫描和磁共振成像显示右侧颞叶有与出血相关的变化,但基底节或中脑无异常。左旋多巴治疗在开始后的几天内产生了显著改善。我们推测帕金森综合征是由经天幕疝继发的中脑受压所致。尽管帕金森综合征是脑叶脑出血的罕见并发症,但认识到这一点很重要,因为它可能是可治疗的。

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