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输尿管镜治疗小型、疼痛性、非梗阻性肾结石患者:小结石综合征

Ureteroscopic treatment of patients with small, painful, non-obstructing renal stones: the small stone syndrome.

作者信息

Jura Ying H, Lahey Susan, Eisner Brian H, Dretler Stephen P

机构信息

Department of Urology, Massachusetts General Hospital, Boston, MA, USA.

出版信息

Clin Nephrol. 2013 Jan;79(1):45-9. doi: 10.5414/CN107637.

Abstract

AIMS

Although it is thought that renal colic results from urinary tract obstruction, some patients evaluated for renal colic are found to have no source for their pain other than small, non-obstructing renal calyceal stones. We refer to this as "the small stone syndrome". We aim to determine if small non-obstructing calyceal stones may also cause pain and that treatment may relieve this pain.

METHOD

A retrospective chart review was performed to identify patients with non-obstructing calyceal stones (≤ 4 mm in diameter) evaluated for flank pain and treated by ureteroscopy. Patients completed a follow-up questionnaire regarding pre- and postoperative pain and quality of life (QOL).

RESULTS

13 patients were included in the analysis. Mean stone diameter was 3 mm (range 1.5 - 4.0 mm). Following ureteroscopy, 11 (85%) patients reported complete resolution of pain and 2 (15%) reported partial resolution. 12 patients were able to describe preoperative and postoperative QOL and of these, 8 (67%) had improved QOL, 4 (33%) had no change, and none reported worsening. Follow-up imaging was available in 10 patients: stone free in 6 (60%), reduction in stone size in 3 (30%), and stone unchanged in 1 (10%).

CONCLUSIONS

Ureteroscopic treatment of painful small, non-obstructing renal calyceal stones achieved complete or partial resolution of pain in all patients and improvement in QOL in a majority of patients.

摘要

目的

尽管人们认为肾绞痛是由尿路梗阻引起的,但一些因肾绞痛接受评估的患者除了存在小的、无梗阻的肾盏结石外,未发现其他疼痛来源。我们将此称为“小结石综合征”。我们旨在确定小的无梗阻肾盏结石是否也会引起疼痛,以及治疗是否可以缓解这种疼痛。

方法

进行一项回顾性病历审查,以确定因胁腹痛接受评估并通过输尿管镜治疗的无梗阻肾盏结石(直径≤4毫米)患者。患者完成了一份关于术前和术后疼痛及生活质量(QOL)的随访问卷。

结果

13名患者纳入分析。结石平均直径为3毫米(范围1.5 - 4.0毫米)。输尿管镜检查后,11名(85%)患者报告疼痛完全缓解,2名(15%)报告部分缓解。12名患者能够描述术前和术后的生活质量,其中8名(67%)生活质量有所改善,4名(33%)无变化,无人报告恶化。10名患者有随访影像:6名(60%)结石清除,3名(30%)结石尺寸减小,1名(10%)结石无变化。

结论

输尿管镜治疗疼痛性小的无梗阻肾盏结石使所有患者的疼痛完全或部分缓解,大多数患者的生活质量得到改善。

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