Kotteas Elias, Ioachim Eli, Pavlidis Nicholas
Department of Medical Oncology, School of Medicine, University of Ioannina, Greece.
Onkologie. 2012;35(9):517-9. doi: 10.1159/000341830. Epub 2012 Aug 20.
Coexistence of an adrenocortical carcinoma and pregnancy is extremely rare with only 25 described cases so far, and has a poor prognosis.
We report the case of a 28-year-old patient with adrenocortical carcinoma initially presenting with Cushing's syndrome and pre-eclampsia in the 22nd week of gestation, treated in our department. She underwent adrenalectomy, but eventually died from metastatic disease. We focus on existing treatment options and concerns for this rare malignancy during pregnancy.
Early diagnosis and surgery are the cornerstones for better outcome.
肾上腺皮质癌与妊娠并存极为罕见，迄今为止仅有25例相关病例报道，且预后较差。
我们报告一例28岁肾上腺皮质癌患者，该患者在妊娠22周时最初表现为库欣综合征和先兆子痫，在我院接受治疗。她接受了肾上腺切除术，但最终死于转移性疾病。我们重点关注了针对孕期这种罕见恶性肿瘤的现有治疗方案及相关问题。
早期诊断和手术是取得更好预后的基石。
