Department of Emergency Medicine, College of Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
J Gastrointest Surg. 2012 Dec;16(12):2274-9. doi: 10.1007/s11605-012-2032-1. Epub 2012 Sep 25.
Success in nonoperative management is only based on the clinical symptoms of patients with acute appendicitis. However, imaging studies can provide further insight into the status of the appendix to monitor treatment response if immediate appendectomy is not undertaken. This study investigates sonographic resolution following nonoperative management and assesses the feasibility of incorporating ultrasound into patient care.
Adult patients with acute appendicitis who had been successfully treated with nonoperative management were enrolled and received repeat sonographic examinations using 3-day intervals until sonographic resolution. The relationship between the time to achieve sonographic resolution and clinical parameters was identified using negative binomial regression models.
From January 2003 to December 2009, 128 patients were successfully treated with nonoperative management. Eighty patients completed sonographic examinations until achieving resolution. Sonographic resolution was achieved on 17 ± 12 days (range, 3-69 days). Ninety-five percent of the patients achieved sonographic resolution within 41 days. The appendicolith was positively related to the time to achieve sonographic resolution (rate ratios, 1.63; 95 % confidence intervals, 1.06-2.51).
Ultrasound can be used to evaluate the condition of the appendix to monitor treatment response following nonoperative management on the sixth week. An appendicolith delays sonographic resolution of appendicitis.
非手术治疗的成功仅基于急性阑尾炎患者的临床症状。然而,如果不立即进行阑尾切除术,影像学研究可以提供有关阑尾状况的进一步信息,以监测治疗反应。本研究调查了非手术治疗后超声的分辨率,并评估了将超声纳入患者护理的可行性。
成功接受非手术治疗的急性阑尾炎成年患者入组并接受重复超声检查,间隔 3 天,直至超声分辨率。使用负二项回归模型确定达到超声分辨率的时间与临床参数之间的关系。
2003 年 1 月至 2009 年 12 月,128 例患者成功接受非手术治疗。80 例患者完成了超声检查直至达到分辨率。超声分辨率在 17 ± 12 天(范围为 3-69 天)内达到。95%的患者在 41 天内达到超声分辨率。阑尾结石与达到超声分辨率的时间呈正相关(比率比,1.63;95%置信区间,1.06-2.51)。
超声可用于评估阑尾状况,以监测非手术治疗后治疗反应。阑尾结石会延迟阑尾炎的超声分辨率。