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Glomerular diseases: podocyte hypertrophy mismatch and glomerular disease.

作者信息

Kriz Wilhelm

出版信息

Nat Rev Nephrol. 2012 Nov;8(11):618-9. doi: 10.1038/nrneph.2012.198. Epub 2012 Sep 25.

DOI:10.1038/nrneph.2012.198
PMID:23007616
Abstract
摘要

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Pathogenic role of TGF-β in the progression of podocyte diseases.TGF-β 在足细胞疾病进展中的致病作用。
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3
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4
[The role of podocyte injury in chronic kidney disease].[足细胞损伤在慢性肾脏病中的作用]
Nihon Rinsho Meneki Gakkai Kaishi. 2015;38(1):26-36. doi: 10.2177/jsci.38.26.
5
OPN deficiency results in severe glomerulosclerosis in uninephrectomized mice.OPN 缺乏导致单侧肾切除小鼠严重的肾小球硬化。
Am J Physiol Renal Physiol. 2013 Jun 15;304(12):F1458-70. doi: 10.1152/ajprenal.00615.2012. Epub 2013 Apr 3.
6
Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction.与衰老大鼠肾小球增大和肾小球硬化相关的足细胞肥大、“适应”及“失代偿”:热量限制的预防作用
J Am Soc Nephrol. 2005 Oct;16(10):2953-66. doi: 10.1681/ASN.2005050488. Epub 2005 Aug 24.
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Glomerular hypertrophy precedes albuminuria and segmental loss of podoplanin in podocytes in Munich-Wistar-Frömter rats.在慕尼黑-维斯塔尔-弗勒姆特大鼠中,肾小球肥大先于蛋白尿以及足细胞中血小板内皮细胞黏附分子-1的节段性缺失出现。
Am J Physiol Renal Physiol. 2008 Apr;294(4):F758-67. doi: 10.1152/ajprenal.00457.2007. Epub 2008 Jan 16.
8
Glomerular Aging and Focal Global Glomerulosclerosis: A Podometric Perspective.肾小球衰老与局灶节段性肾小球硬化:足细胞计量学视角
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Analysis of ultrastructural glomerular basement membrane lesions and podocytes associated with proteinuria and sclerosis in Osborne-Mendel rats with progressive glomerulonephropathy.对患有进行性肾小球肾炎的奥斯本-孟德尔大鼠中与蛋白尿和硬化相关的肾小球基底膜超微结构病变及足细胞的分析。
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The podocyte's response to injury: role in proteinuria and glomerulosclerosis.足细胞对损伤的反应:在蛋白尿和肾小球硬化中的作用。
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1
Growth-dependent podocyte failure causes glomerulosclerosis.生长依赖性足细胞衰竭导致肾小球硬化。
J Am Soc Nephrol. 2012 Aug;23(8):1351-63. doi: 10.1681/ASN.2012030271. Epub 2012 Jul 5.
2
Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations.探讨肾小球肥大的定义:临床病理与方法学的考虑。
Nephrol Dial Transplant. 2011 Jul;26(7):2202-8. doi: 10.1093/ndt/gfq688. Epub 2010 Nov 29.
3
Cumulative excretion of urinary podocytes reflects disease progression in IgA nephropathy and Schönlein-Henoch purpura nephritis.
糖尿病肾病中,一种新的足细胞相关蛋白——盘状结构域受体 2 相关激活蛋白增多。
Nephrol Dial Transplant. 2021 May 27;36(6):1006-1016. doi: 10.1093/ndt/gfab014.
4
Roles of Hydrogen Sulfide Donors in Common Kidney Diseases.硫化氢供体在常见肾脏疾病中的作用
Front Pharmacol. 2020 Nov 19;11:564281. doi: 10.3389/fphar.2020.564281. eCollection 2020.
5
APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy.APOL1-G0 可保护 HIV 相关肾病小鼠模型中的足细胞。
PLoS One. 2019 Oct 29;14(10):e0224408. doi: 10.1371/journal.pone.0224408. eCollection 2019.
6
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.mTOR 介导的足细胞肥大调节小鼠和人类的肾小球完整性。
JCI Insight. 2019 Sep 19;4(18):99271. doi: 10.1172/jci.insight.99271.
7
Adiponectin for the treatment of diabetic nephropathy.脂联素治疗糖尿病肾病。
Korean J Intern Med. 2019 May;34(3):480-491. doi: 10.3904/kjim.2019.109. Epub 2019 Apr 30.
8
Novel Actions of Growth Hormone in Podocytes: Implications for Diabetic Nephropathy.生长激素在足细胞中的新作用:对糖尿病肾病的影响。
Front Med (Lausanne). 2017 Jul 12;4:102. doi: 10.3389/fmed.2017.00102. eCollection 2017.
9
FSGS as an Adaptive Response to Growth-Induced Podocyte Stress.局灶节段性肾小球硬化是对生长诱导的足细胞应激的适应性反应。
J Am Soc Nephrol. 2017 Oct;28(10):2931-2945. doi: 10.1681/ASN.2017020174. Epub 2017 Jul 18.
10
The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development.斑马鱼肾脏突变体齐柏林飞艇表明,brca2/fancd1对前肾发育至关重要。
Dev Biol. 2017 Aug 1;428(1):148-163. doi: 10.1016/j.ydbio.2017.05.025. Epub 2017 Jun 1.
尿足细胞的累积排泄反映了IgA肾病和过敏性紫癜性肾炎的疾病进展。
Clin J Am Soc Nephrol. 2007 Mar;2(2):231-8. doi: 10.2215/CJN.01470506. Epub 2007 Jan 31.
4
Pathways to nephron loss starting from glomerular diseases-insights from animal models.从肾小球疾病开始的肾单位丢失途径——来自动物模型的见解
Kidney Int. 2005 Feb;67(2):404-19. doi: 10.1111/j.1523-1755.2005.67097.x.
5
The role of VEGF-A in glomerular development and function.血管内皮生长因子A(VEGF-A)在肾小球发育及功能中的作用。
Curr Opin Nephrol Hypertens. 2004 Jan;13(1):9-15. doi: 10.1097/00041552-200401000-00002.
6
Urinary excretion of viable podocytes in health and renal disease.健康及肾脏疾病状态下活的足细胞的尿排泄情况。
Am J Physiol Renal Physiol. 2003 Jul;285(1):F40-8. doi: 10.1152/ajprenal.00404.2002. Epub 2003 Mar 11.
7
Progression of glomerular diseases: is the podocyte the culprit?
Kidney Int. 1998 Sep;54(3):687-97. doi: 10.1046/j.1523-1755.1998.00044.x.
8
Long-term treatment of rats with FGF-2 results in focal segmental glomerulosclerosis.用成纤维细胞生长因子-2对大鼠进行长期治疗会导致局灶节段性肾小球硬化。
Kidney Int. 1995 Nov;48(5):1435-50. doi: 10.1038/ki.1995.433.
9
Nephron adaptation to renal injury or ablation.肾单位对肾损伤或肾切除的适应性变化。
Am J Physiol. 1985 Sep;249(3 Pt 2):F324-37. doi: 10.1152/ajprenal.1985.249.3.F324.
10
Glomerular damage after uninephrectomy in young rats. II. Mechanical stress on podocytes as a pathway to sclerosis.幼鼠单侧肾切除术后的肾小球损伤。II. 足细胞上的机械应力作为硬化的一条途径。
Kidney Int. 1992 Jul;42(1):148-60. doi: 10.1038/ki.1992.272.