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本文引用的文献

1
Small bowel angiodysplasia in a patient on haemodialysis: difficulties in diagnosis and management.一名血液透析患者的小肠血管发育异常:诊断和管理中的困难
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0542. Epub 2009 Mar 27.
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Vascular lesions of the gastrointestinal tract.胃肠道血管病变
Best Pract Res Clin Gastroenterol. 2008;22(2):313-28. doi: 10.1016/j.bpg.2007.10.026.
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Successful management of patients with a drug-eluting coronary stent presenting for elective, non-cardiac surgery.药物洗脱冠状动脉支架置入患者择期非心脏手术的成功管理。
Br J Anaesth. 2007 Jan;98(1):19-22. doi: 10.1093/bja/ael318. Epub 2006 Nov 22.
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Late thrombosis of sirolimus-eluting stents following noncardiac surgery.非心脏手术后西罗莫司洗脱支架的晚期血栓形成
Catheter Cardiovasc Interv. 2005 Aug;65(4):516-9. doi: 10.1002/ccd.20391.
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Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents.药物洗脱支架成功植入后血栓形成的发生率、预测因素及转归
JAMA. 2005 May 4;293(17):2126-30. doi: 10.1001/jama.293.17.2126.
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Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy.停用抗血小板治疗后药物洗脱冠状动脉支架的晚期血栓形成。
Lancet. 2004;364(9444):1519-21. doi: 10.1016/S0140-6736(04)17275-9.
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Drug-eluting stents: some bare facts.药物洗脱支架:一些基本事实。
Lancet. 2004;364(9444):1466-7. doi: 10.1016/S0140-6736(04)17287-5.
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Clinical outcome of patients undergoing non-cardiac surgery in the two months following coronary stenting.
J Am Coll Cardiol. 2003 Jul 16;42(2):234-40. doi: 10.1016/s0735-1097(03)00622-3.
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Catastrophic outcomes of noncardiac surgery soon after coronary stenting.
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在植入药物洗脱冠状动脉支架后立即开始双联抗血小板治疗的患者中成功切除复杂的空肠出血性动静脉畸形。

Successful resection of complicated bleeding arteriovenous malformation of the jejunum in patients starting dual-antiplatelet therapy just after implanting a drug-eluting coronary stent.

作者信息

Fujikawa Takahisa, Maekawa Hisatsugu, Shiraishi Kei, Tanaka Akira

机构信息

Department of Surgery, Kokura Memorial Hospital, Kitakyushu, Fukuoka, Japan.

出版信息

BMJ Case Rep. 2012 Sep 24;2012:bcr2012006779. doi: 10.1136/bcr-2012-006779.

DOI:10.1136/bcr-2012-006779
PMID:23008375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4543713/
Abstract

We report a case of a 57-year-old man who started dual-antiplatelet therapy with aspirin and clopidogrel following implantation of drug-eluting coronary stent and developed persistent active gastrointestinal bleeding. After detecting the origin of bleeding by double-balloon enteroscopy, successful laparoscopy-assisted partial jejunal resection was performed and the patient condition was promptly recovered, without any thrombotic or bleeding complications. Pathology revealed arteriovenous malformation of the jejunum without any malignancy. We should care for and be aware of this lesion as a rare cause of gastrointestinal bleeding when strong antithrombotic therapy is initiated. Under rigorous assessment and perioperative management, as well as meticulous intraoperative dissection and haemostasis, satisfactory outcome was achieved even in this complicated situation.

摘要

我们报告一例57岁男性患者,在植入药物洗脱冠状动脉支架后开始使用阿司匹林和氯吡格雷进行双联抗血小板治疗,并出现持续性活动性胃肠道出血。通过双气囊小肠镜检查发现出血源后,成功进行了腹腔镜辅助部分空肠切除术,患者病情迅速恢复,无任何血栓形成或出血并发症。病理显示空肠动静脉畸形,无任何恶性病变。当启动强化抗栓治疗时,我们应关注并意识到这种病变是胃肠道出血的罕见原因。在严格的评估和围手术期管理以及细致的术中解剖和止血操作下,即使在这种复杂情况下也取得了满意的结果。