University of Duisburg-Essen, Essen, Germany.
BMC Complement Altern Med. 2012 Sep 25;12:162. doi: 10.1186/1472-6882-12-162.
Mindfulness-based stress reduction (MBSR) is frequently used for pain conditions. While systematic reviews on MBSR for chronic pain have been conducted, there are no reviews for specific pain conditions. Therefore a systematic review of the effectiveness of MBSR in low back pain was performed.
MEDLINE, the Cochrane Library, EMBASE, CAMBASE, and PsycInfo were screened through November 2011. The search strategy combined keywords for MBSR with keywords for low back pain. Randomized controlled trials (RCTs) comparing MBSR to control conditions in patients with low back pain were included. Two authors independently assessed risk of bias using the Cochrane risk of bias tool. Clinical importance of group differences was assessed for the main outcome measures pain intensity and back-specific disability.
Three RCTs with a total of 117 chronic low back pain patients were included. One RCT on failed back surgery syndrome reported significant and clinically important short-term improvements in pain intensity and disability for MBSR compared to no treatment. Two RCTs on older adults (age ≥ 65 years) with chronic specific or non-specific low back pain reported no short-term or long-term improvements in pain or disability for MBSR compared to no treatment or health education. Two RCTs reported larger short-term improvements of pain acceptance for MBSR compared to no treatment.
This review found inconclusive evidence of effectiveness of MBSR in improving pain intensity or disability in chronic low back pain patients. However, there is limited evidence that MBSR can improve pain acceptance. Further RCTs with larger sample sizes, adequate control interventions, and longer follow-ups are needed before firm conclusions can be drawn.
基于正念减压(MBSR)常用于治疗疼痛病症。虽然已对慢性疼痛的 MBSR 进行了系统评价,但针对特定疼痛病症的评价尚未见报道。因此,本文对 MBSR 治疗腰痛的疗效进行了系统评价。
通过 MEDLINE、Cochrane 图书馆、EMBASE、CAMBASE 和 PsycInfo 数据库进行了截至 2011 年 11 月的检索。检索策略将 MBSR 的关键词与腰痛的关键词相结合。纳入的研究为 MBSR 与腰痛对照条件相比的随机对照试验(RCT)。两位作者独立使用 Cochrane 偏倚风险工具评估了偏倚风险。对主要结局指标疼痛强度和腰痛特异性残疾的组间差异,评估了临床重要性。
纳入的 3 项 RCT 共 117 例慢性腰痛患者。1 项关于失败的腰椎手术综合征的 RCT 报道,与不治疗相比,MBSR 在短期可显著改善疼痛强度和残疾程度,且具有临床意义。2 项关于老年(年龄≥65 岁)慢性特异性或非特异性腰痛患者的 RCT 报道,与不治疗或健康教育相比,MBSR 在短期或长期均不能改善疼痛或残疾程度。2 项 RCT 报道 MBSR 与不治疗相比可在短期内更显著地改善疼痛接受度。
本综述发现,MBSR 在改善慢性腰痛患者的疼痛强度或残疾程度方面的疗效证据尚不明确。然而,有有限的证据表明 MBSR 可改善疼痛接受度。需要进一步开展具有更大样本量、适当对照干预和更长随访时间的 RCT 来得出更确切的结论。